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Assessment of QT-measurement accuracy using the 12-lead electrocardiogram derived from EASI leads

Martinez, Juan Pablo; Laguna, Pablo; Olmos, Salvador; Pahlm, Olle LU ; Pettersson, Jonas and Sörnmo, Leif LU (2007) In Journal of Electrocardiology 40(2). p.172-179
Abstract
The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the 2 sets of measurements was quantified both on a lead-by-lead basis and a multilead basis with global definitions of QRS onset and T-wave end. The results show that the agreement between QT-interval measurements from the 2 lead systems is acceptable, with negligible mean differences and with correlation coefficients ranging from 0.91 to 0.98 depending on the lead studied. Although the SD shows a clear dependence... (More)
The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the 2 sets of measurements was quantified both on a lead-by-lead basis and a multilead basis with global definitions of QRS onset and T-wave end. The results show that the agreement between QT-interval measurements from the 2 lead systems is acceptable, with negligible mean differences and with correlation coefficients ranging from 0.91 to 0.98 depending on the lead studied. Although the SD shows a clear dependence on the selected lead (ranging from 9.2 to 26.4 milliseconds), differences are within the accepted tolerances for automatic delineation. In a few patients, large differences were found, mainly because of changes in morphology present in both lead systems. QT intervals measured by the multilead approach were considerably more stable than single-lead measurements and resulted in a much better agreement between the 2 lead systems (correlation coefficient, 0.98; QT difference, 1.1 +/- 9.8 milliseconds). Thus, the EASI 12-lead ECG may be used for reliable QT monitoring when the multilead delineation approach is adopted. (c) 2007 Elsevier Inc. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Electrocardiology
volume
40
issue
2
pages
172 - 179
publisher
Elsevier
external identifiers
  • wos:000245166900015
  • scopus:33847610152
ISSN
1532-8430
DOI
10.1016/j.jelectrocard.2006.08.089
language
English
LU publication?
yes
id
ee7127c3-c8a8-44e4-9109-1f20acc9699f (old id 670422)
date added to LUP
2007-12-14 16:39:27
date last changed
2017-04-23 03:30:02
@article{ee7127c3-c8a8-44e4-9109-1f20acc9699f,
  abstract     = {The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the 2 sets of measurements was quantified both on a lead-by-lead basis and a multilead basis with global definitions of QRS onset and T-wave end. The results show that the agreement between QT-interval measurements from the 2 lead systems is acceptable, with negligible mean differences and with correlation coefficients ranging from 0.91 to 0.98 depending on the lead studied. Although the SD shows a clear dependence on the selected lead (ranging from 9.2 to 26.4 milliseconds), differences are within the accepted tolerances for automatic delineation. In a few patients, large differences were found, mainly because of changes in morphology present in both lead systems. QT intervals measured by the multilead approach were considerably more stable than single-lead measurements and resulted in a much better agreement between the 2 lead systems (correlation coefficient, 0.98; QT difference, 1.1 +/- 9.8 milliseconds). Thus, the EASI 12-lead ECG may be used for reliable QT monitoring when the multilead delineation approach is adopted. (c) 2007 Elsevier Inc. All rights reserved.},
  author       = {Martinez, Juan Pablo and Laguna, Pablo and Olmos, Salvador and Pahlm, Olle and Pettersson, Jonas and Sörnmo, Leif},
  issn         = {1532-8430},
  language     = {eng},
  number       = {2},
  pages        = {172--179},
  publisher    = {Elsevier},
  series       = {Journal of Electrocardiology},
  title        = {Assessment of QT-measurement accuracy using the 12-lead electrocardiogram derived from EASI leads},
  url          = {http://dx.doi.org/10.1016/j.jelectrocard.2006.08.089},
  volume       = {40},
  year         = {2007},
}