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Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging

Wilm, B. J.; Svensson, Jonas LU ; Henning, A.; Pruessmann, K. P.; Boesiger, P. and Kollias, S. S. (2007) In Magnetic Resonance in Medicine 57(3). p.625-630
Abstract
A spin-echo single-shot echo-planar imaging (SS-EPI) technique with a reduced field of view (FOV) in the phase-encoding direction is presented that simultaneously reduces susceptibility effects and motion artifacts in diffusion-weighted (DW) imaging (DWI) of the spinal cord at a high field strength (3T). To minimize aliasing, an outer volume suppression (OVS) sequence was implemented. Effective fat suppression was achieved with the use of a slice-selection gradient-reversal technique. The OVS was optimized by numerical simulations with respect to T-1 relaxation times and B-1 variations. The optimized sequence was evaluated in vitro and in vivo. In simulations the optimized OVS showed suppression to < 0.25% and similar to 3% in an... (More)
A spin-echo single-shot echo-planar imaging (SS-EPI) technique with a reduced field of view (FOV) in the phase-encoding direction is presented that simultaneously reduces susceptibility effects and motion artifacts in diffusion-weighted (DW) imaging (DWI) of the spinal cord at a high field strength (3T). To minimize aliasing, an outer volume suppression (OVS) sequence was implemented. Effective fat suppression was achieved with the use of a slice-selection gradient-reversal technique. The OVS was optimized by numerical simulations with respect to T-1 relaxation times and B-1 variations. The optimized sequence was evaluated in vitro and in vivo. In simulations the optimized OVS showed suppression to < 0.25% and similar to 3% in an optimal and worst-case scenario, respectively. In vitro measurements showed a mean residual signal of < 0.95% +/- 0.42 for all suppressed areas. In vivo acquisition with 0.9 x 1.05 mm(2) in-plane resolution resulted in artifact-free images. The short imaging time of this technique makes it promising for clinical studies. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
outer volume suppression, reduced FOV, spinal cord, diffusion imaging, DTI
in
Magnetic Resonance in Medicine
volume
57
issue
3
pages
625 - 630
publisher
Wiley Online Library
external identifiers
  • wos:000244657200022
  • scopus:33847725167
ISSN
1522-2594
DOI
10.1002/mrm.21167
language
English
LU publication?
yes
id
fe74bed2-c31f-4991-a0fb-40f0a065c898 (old id 671605)
date added to LUP
2007-12-19 09:03:51
date last changed
2017-10-01 03:48:17
@article{fe74bed2-c31f-4991-a0fb-40f0a065c898,
  abstract     = {A spin-echo single-shot echo-planar imaging (SS-EPI) technique with a reduced field of view (FOV) in the phase-encoding direction is presented that simultaneously reduces susceptibility effects and motion artifacts in diffusion-weighted (DW) imaging (DWI) of the spinal cord at a high field strength (3T). To minimize aliasing, an outer volume suppression (OVS) sequence was implemented. Effective fat suppression was achieved with the use of a slice-selection gradient-reversal technique. The OVS was optimized by numerical simulations with respect to T-1 relaxation times and B-1 variations. The optimized sequence was evaluated in vitro and in vivo. In simulations the optimized OVS showed suppression to &lt; 0.25% and similar to 3% in an optimal and worst-case scenario, respectively. In vitro measurements showed a mean residual signal of &lt; 0.95% +/- 0.42 for all suppressed areas. In vivo acquisition with 0.9 x 1.05 mm(2) in-plane resolution resulted in artifact-free images. The short imaging time of this technique makes it promising for clinical studies.},
  author       = {Wilm, B. J. and Svensson, Jonas and Henning, A. and Pruessmann, K. P. and Boesiger, P. and Kollias, S. S.},
  issn         = {1522-2594},
  keyword      = {outer volume suppression,reduced FOV,spinal cord,diffusion imaging,DTI},
  language     = {eng},
  number       = {3},
  pages        = {625--630},
  publisher    = {Wiley Online Library},
  series       = {Magnetic Resonance in Medicine},
  title        = {Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging},
  url          = {http://dx.doi.org/10.1002/mrm.21167},
  volume       = {57},
  year         = {2007},
}