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Alignment of a conjugated polymer onto amyloid-like protein fibrils

Herland, Anna; Bjork, Per; Hania, Ralph LU ; Scheblykin, Ivan LU and Inganas, Olle (2007) In Small 3(2). p.318-325
Abstract
The amyloid-like fibril is a biomolecular nanowire template of very high stability. Here we describe the coordination of a conjugated polyelectrolyte, poly(thiophene acetic acid) (PTAA), to bovine insulin fibrils with widths of < 10 nm and lengths of up to more than 10 mu m. Fibrils complexed with PTAA are aligned on surfaces through molecular combing and transfer printing. Single-molecule spectroscopy techniques are applied to chart spectral variation in the emission of these wires. When these results are combined with analysis of the polarization of the emitted light, we can conclude that the polymer chains are preferentially aligned along the fibrillar axis.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
self-assembly, polymers, fibrils, nanowires, template synthesis
in
Small
volume
3
issue
2
pages
318 - 325
publisher
John Wiley & Sons
external identifiers
  • wos:000244207900024
  • scopus:33847027742
ISSN
1613-6829
DOI
10.1002/smll.200600377
language
English
LU publication?
yes
id
55a50bb9-4687-488c-b701-102cac9081ce (old id 674411)
date added to LUP
2007-12-11 10:02:09
date last changed
2017-07-23 03:48:10
@article{55a50bb9-4687-488c-b701-102cac9081ce,
  abstract     = {The amyloid-like fibril is a biomolecular nanowire template of very high stability. Here we describe the coordination of a conjugated polyelectrolyte, poly(thiophene acetic acid) (PTAA), to bovine insulin fibrils with widths of &lt; 10 nm and lengths of up to more than 10 mu m. Fibrils complexed with PTAA are aligned on surfaces through molecular combing and transfer printing. Single-molecule spectroscopy techniques are applied to chart spectral variation in the emission of these wires. When these results are combined with analysis of the polarization of the emitted light, we can conclude that the polymer chains are preferentially aligned along the fibrillar axis.},
  author       = {Herland, Anna and Bjork, Per and Hania, Ralph and Scheblykin, Ivan and Inganas, Olle},
  issn         = {1613-6829},
  keyword      = {self-assembly,polymers,fibrils,nanowires,template synthesis},
  language     = {eng},
  number       = {2},
  pages        = {318--325},
  publisher    = {John Wiley & Sons},
  series       = {Small},
  title        = {Alignment of a conjugated polymer onto amyloid-like protein fibrils},
  url          = {http://dx.doi.org/10.1002/smll.200600377},
  volume       = {3},
  year         = {2007},
}