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Ultramicrobiosensor for the selective detection of glutamate

Schuvailo, Oleg M. ; Gaspar, Szilveszter LU ; Soldatkin, Alexey P. and Csöregi, Elisabeth LU (2007) In Electroanalysis 19(1). p.71-78
Abstract
Carbon fiber microelectrodes, able to detect catecholamine release from single cells, have significantly contributed to our present understanding of the mechanism of secretory neurotransmission. In spite of their obvious advantages, there are only a few amperometric sensors (characterized by appropriate size, sensitivity, and selectivity) able to measure the release of other (not easily oxidizable) neurotransmitters at cellular level. The present work describes the fabrication and characterization of an ultramicrobiosensor for the selective detection of glutamate. ne developed sensor has a size of 2.5 - 15 mu m in diameter, a sensitivity of 0.62 mA mM(-1) cm(-2), and a detection limit of 5 mu M. The excellent selectivity of the sensor... (More)
Carbon fiber microelectrodes, able to detect catecholamine release from single cells, have significantly contributed to our present understanding of the mechanism of secretory neurotransmission. In spite of their obvious advantages, there are only a few amperometric sensors (characterized by appropriate size, sensitivity, and selectivity) able to measure the release of other (not easily oxidizable) neurotransmitters at cellular level. The present work describes the fabrication and characterization of an ultramicrobiosensor for the selective detection of glutamate. ne developed sensor has a size of 2.5 - 15 mu m in diameter, a sensitivity of 0.62 mA mM(-1) cm(-2), and a detection limit of 5 mu M. The excellent selectivity of the sensor (achieved using electrodeposition of Ru, Rh, and poly(m-phenylenediamine)) makes it a promising candidate for monitoring glutamate release at single cell level. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
interference elimination, glutamate detection, microbiosensor, amperometry, ultramicroelectrode
in
Electroanalysis
volume
19
issue
1
pages
71 - 78
publisher
John Wiley and Sons
external identifiers
  • wos:000243443000010
  • scopus:33846442796
ISSN
1040-0397
DOI
10.1002/elan.200603707
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
id
cb0de7cb-87b9-4e80-ac8d-96e1a912cb53 (old id 677426)
date added to LUP
2016-04-01 16:53:02
date last changed
2021-01-06 05:37:58
@article{cb0de7cb-87b9-4e80-ac8d-96e1a912cb53,
  abstract     = {Carbon fiber microelectrodes, able to detect catecholamine release from single cells, have significantly contributed to our present understanding of the mechanism of secretory neurotransmission. In spite of their obvious advantages, there are only a few amperometric sensors (characterized by appropriate size, sensitivity, and selectivity) able to measure the release of other (not easily oxidizable) neurotransmitters at cellular level. The present work describes the fabrication and characterization of an ultramicrobiosensor for the selective detection of glutamate. ne developed sensor has a size of 2.5 - 15 mu m in diameter, a sensitivity of 0.62 mA mM(-1) cm(-2), and a detection limit of 5 mu M. The excellent selectivity of the sensor (achieved using electrodeposition of Ru, Rh, and poly(m-phenylenediamine)) makes it a promising candidate for monitoring glutamate release at single cell level.},
  author       = {Schuvailo, Oleg M. and Gaspar, Szilveszter and Soldatkin, Alexey P. and Csöregi, Elisabeth},
  issn         = {1040-0397},
  language     = {eng},
  number       = {1},
  pages        = {71--78},
  publisher    = {John Wiley and Sons},
  series       = {Electroanalysis},
  title        = {Ultramicrobiosensor for the selective detection of glutamate},
  url          = {http://dx.doi.org/10.1002/elan.200603707},
  doi          = {10.1002/elan.200603707},
  volume       = {19},
  year         = {2007},
}