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The enzyme thermistor-A realistic biosensor concept. A critical review.

Yakovleva, Maria LU ; Bhand, Sunil and Danielsson, Bengt (2013) In Analytica Chimica Acta 766. p.1-12
Abstract
This review describes principles and features of thermal biosensors and microbiosensors in flow injection analysis. Examples are given that illustrate the great versatility and excellent operational stability offered by thermal biosensors. The examples are mostly from work with the original type of enzyme thermistor operating with an enzyme column, but there will also be work described involving miniaturised devices including thermal lab-on-chip constructions and other types of sensing materials, such as MIPs (molecularly imprinted polymers) for both affinity and catalytic reactions. Several recently presented thermal biosensor concepts are reviewed including a thermal-electrochemical hybrid sensor for lactose based on immobilised... (More)
This review describes principles and features of thermal biosensors and microbiosensors in flow injection analysis. Examples are given that illustrate the great versatility and excellent operational stability offered by thermal biosensors. The examples are mostly from work with the original type of enzyme thermistor operating with an enzyme column, but there will also be work described involving miniaturised devices including thermal lab-on-chip constructions and other types of sensing materials, such as MIPs (molecularly imprinted polymers) for both affinity and catalytic reactions. Several recently presented thermal biosensor concepts are reviewed including a thermal-electrochemical hybrid sensor for lactose based on immobilised cellobiose dehydrogenase. Another recent method is the determination of fructose using a fructose-6-phosphate kinase column. Operation with complex sample matrices such as blood, plasma and milk and how to avoid non-specific temperature effects are considered. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Analytica Chimica Acta
volume
766
pages
1 - 12
publisher
Elsevier
external identifiers
  • wos:000315834100001
  • pmid:23427796
  • scopus:84874246825
  • pmid:23427796
ISSN
1873-4324
DOI
10.1016/j.aca.2012.12.004
language
English
LU publication?
yes
id
67cdc222-5092-4d5f-9497-94bdefd81563 (old id 3559546)
date added to LUP
2016-04-01 09:56:03
date last changed
2023-11-09 07:51:35
@article{67cdc222-5092-4d5f-9497-94bdefd81563,
  abstract     = {{This review describes principles and features of thermal biosensors and microbiosensors in flow injection analysis. Examples are given that illustrate the great versatility and excellent operational stability offered by thermal biosensors. The examples are mostly from work with the original type of enzyme thermistor operating with an enzyme column, but there will also be work described involving miniaturised devices including thermal lab-on-chip constructions and other types of sensing materials, such as MIPs (molecularly imprinted polymers) for both affinity and catalytic reactions. Several recently presented thermal biosensor concepts are reviewed including a thermal-electrochemical hybrid sensor for lactose based on immobilised cellobiose dehydrogenase. Another recent method is the determination of fructose using a fructose-6-phosphate kinase column. Operation with complex sample matrices such as blood, plasma and milk and how to avoid non-specific temperature effects are considered.}},
  author       = {{Yakovleva, Maria and Bhand, Sunil and Danielsson, Bengt}},
  issn         = {{1873-4324}},
  language     = {{eng}},
  pages        = {{1--12}},
  publisher    = {{Elsevier}},
  series       = {{Analytica Chimica Acta}},
  title        = {{The enzyme thermistor-A realistic biosensor concept. A critical review.}},
  url          = {{http://dx.doi.org/10.1016/j.aca.2012.12.004}},
  doi          = {{10.1016/j.aca.2012.12.004}},
  volume       = {{766}},
  year         = {{2013}},
}