Detection of pre-plaque amyloid aggregation using FTIR
Klementieva, Oxana LU
; Engdahl, Anders
LU
; Faideau, Mathilde
LU
; Willén, Katarina
LU
; Uvdal, Per
LU
and Keppler Gouras, Gunnar
LU
(2014)
In Alzheimer's and Dementia
10(4).
- Abstract
- Background: Alzheimer's disease (AD) is characterized by misfolding and aggregation of naturally occurring beta-amyloid peptides (Aβ). These aggregates are thought to be pathogenic to neurons, although the conformation of the pathogenic Aβ species remains unclear. Biochemical extraction methods and different microscopy techniques (TEM, confocal) can be used to identify pathogenic Aβ species in the brain, although such methods can alter protein conformation or are n ot designed to determine structural details of protein assemblies.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/67dea852-554e-4ca2-9a6d-070e6c291907
- author
- Klementieva, Oxana
LU
; Engdahl, Anders
LU
; Faideau, Mathilde
LU
; Willén, Katarina
LU
; Uvdal, Per
LU
and Keppler Gouras, Gunnar
LU
- organization
- publishing date
- 2014-07-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Alzheimer's and Dementia
- volume
- 10
- issue
- 4
- publisher
- Wiley
- ISSN
- 1552-5279
- DOI
- 10.1016/j.jalz.2014.05.1158
- language
- English
- LU publication?
- yes
- id
- 67dea852-554e-4ca2-9a6d-070e6c291907
- date added to LUP
- 2019-09-18 13:02:12
- date last changed
- 2019-10-22 02:21:34
@article{67dea852-554e-4ca2-9a6d-070e6c291907,
abstract = {{Background: Alzheimer's disease (AD) is characterized by misfolding and aggregation of naturally occurring beta-amyloid peptides (Aβ). These aggregates are thought to be pathogenic to neurons, although the conformation of the pathogenic Aβ species remains unclear. Biochemical extraction methods and different microscopy techniques (TEM, confocal) can be used to identify pathogenic Aβ species in the brain, although such methods can alter protein conformation or are n ot designed to determine structural details of protein assemblies.}},
author = {{Klementieva, Oxana and Engdahl, Anders and Faideau, Mathilde and Willén, Katarina and Uvdal, Per and Keppler Gouras, Gunnar}},
issn = {{1552-5279}},
language = {{eng}},
month = {{07}},
number = {{4}},
publisher = {{Wiley}},
series = {{Alzheimer's and Dementia}},
title = {{Detection of pre-plaque amyloid aggregation using FTIR}},
url = {{http://dx.doi.org/10.1016/j.jalz.2014.05.1158}},
doi = {{10.1016/j.jalz.2014.05.1158}},
volume = {{10}},
year = {{2014}},
}