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Antepartum percutaneous renal biopsy

Wide-Swensson, Dag LU ; Strevens, Helena LU and Willner, Julian LU (2007) In International Journal of Gynecology & Obstetrics 98(2). p.88-92
Abstract
Objective: To assess the value and adverse effects of an ultrasound -guided renal biopsy technique in women with normal and pathotogic pregnancies. Method: Biopsy samples were taken from 36 women with hypertensive disease (28 with pre-eclampsia) and 18 healthy pregnant women using a thin needle and an ultrasound -guided biopsy device. Results: Gtomerutar endotheliosis, a structural change typical of pre-eclampsia, was found in all hypertensive women, but it was more pronounced in the 28 pre-eclamptic women than in the 8 women with nonproteinuric hypertension. A similar change, however, was seen in 11 of the 18 controls. One serious adverse event occurred, retroperitoneat hematoma, in the woman with the most severe pre-eclampsia.... (More)
Objective: To assess the value and adverse effects of an ultrasound -guided renal biopsy technique in women with normal and pathotogic pregnancies. Method: Biopsy samples were taken from 36 women with hypertensive disease (28 with pre-eclampsia) and 18 healthy pregnant women using a thin needle and an ultrasound -guided biopsy device. Results: Gtomerutar endotheliosis, a structural change typical of pre-eclampsia, was found in all hypertensive women, but it was more pronounced in the 28 pre-eclamptic women than in the 8 women with nonproteinuric hypertension. A similar change, however, was seen in 11 of the 18 controls. One serious adverse event occurred, retroperitoneat hematoma, in the woman with the most severe pre-eclampsia. Conclusion: Glomerular endotheliosis is not to be considered pathognomonic for pre-eclampsia. Few complications followed renal biopsy in this study, but complications arose in the sickest patient. It is probably not advisable to perform anteparturn renal biopsies in pregnant women with a rapidly deteriorating renal function and swollen kidneys. In these women, the biopsy does not facilitate diagnosis and is hazardous. (c) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. AR rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
pre-eclampsia, pregnancy, hypertension, endotheliosis, human, renal, biopsy
in
International Journal of Gynecology & Obstetrics
volume
98
issue
2
pages
88 - 92
publisher
Elsevier
external identifiers
  • wos:000248878400001
  • scopus:34447263769
ISSN
1879-3479
DOI
10.1016/j.ijgo.2007.03.049
language
English
LU publication?
yes
id
9c6c079e-2c85-4adf-ba96-c90e5d8f7ce9 (old id 688984)
date added to LUP
2007-12-19 16:20:16
date last changed
2017-01-01 04:22:04
@article{9c6c079e-2c85-4adf-ba96-c90e5d8f7ce9,
  abstract     = {Objective: To assess the value and adverse effects of an ultrasound -guided renal biopsy technique in women with normal and pathotogic pregnancies. Method: Biopsy samples were taken from 36 women with hypertensive disease (28 with pre-eclampsia) and 18 healthy pregnant women using a thin needle and an ultrasound -guided biopsy device. Results: Gtomerutar endotheliosis, a structural change typical of pre-eclampsia, was found in all hypertensive women, but it was more pronounced in the 28 pre-eclamptic women than in the 8 women with nonproteinuric hypertension. A similar change, however, was seen in 11 of the 18 controls. One serious adverse event occurred, retroperitoneat hematoma, in the woman with the most severe pre-eclampsia. Conclusion: Glomerular endotheliosis is not to be considered pathognomonic for pre-eclampsia. Few complications followed renal biopsy in this study, but complications arose in the sickest patient. It is probably not advisable to perform anteparturn renal biopsies in pregnant women with a rapidly deteriorating renal function and swollen kidneys. In these women, the biopsy does not facilitate diagnosis and is hazardous. (c) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. AR rights reserved.},
  author       = {Wide-Swensson, Dag and Strevens, Helena and Willner, Julian},
  issn         = {1879-3479},
  keyword      = {pre-eclampsia,pregnancy,hypertension,endotheliosis,human,renal,biopsy},
  language     = {eng},
  number       = {2},
  pages        = {88--92},
  publisher    = {Elsevier},
  series       = {International Journal of Gynecology & Obstetrics},
  title        = {Antepartum percutaneous renal biopsy},
  url          = {http://dx.doi.org/10.1016/j.ijgo.2007.03.049},
  volume       = {98},
  year         = {2007},
}