Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group

Mosca, Andrea ; Goodall, Ian ; Hoshino, Tadao ; Jeppsson, Jan-Olof LU ; John, W. Garry ; Little, Randie R. ; Miedema, Kor ; Myers, Gary L. ; Reinauer, Hans and Sacks, David B. , et al. (2007) In Clinical Chemistry and Laboratory Medicine 45(8). p.1077-1080
Abstract
The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes. There are at least 30 different laboratory assays commercially available to measure the proportion of HbA1c in blood. In 1995 the IFCC established a Working Group (IFCC WG-HbA1c) to achieve international standardization of HbA1c measurement. The main achievements can be summarized as follows: a) a reference measurement procedure has been established with purified primary calibrators; b) a network of reference laboratories has been developed worldwide; and c) work has begun on implementation of traceability to the IFCC reference system. The IFCC WG-HbA1c recognizes the recommendation of the IFCC-IUPAC Committee on Nomenclature,... (More)
The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes. There are at least 30 different laboratory assays commercially available to measure the proportion of HbA1c in blood. In 1995 the IFCC established a Working Group (IFCC WG-HbA1c) to achieve international standardization of HbA1c measurement. The main achievements can be summarized as follows: a) a reference measurement procedure has been established with purified primary calibrators; b) a network of reference laboratories has been developed worldwide; and c) work has begun on implementation of traceability to the IFCC reference system. The IFCC WG-HbA1c recognizes the recommendation of the IFCC-IUPAC Committee on Nomenclature, Properties and Units that the analyte measured by the IFCC reference measurement procedure has been defined as beta N1-deoxyfructosyl-hemoglobin and that the recommended measurement units are mmol/mol. The IFCC WG-HbA1c recommends maintaining the use of the name HbA1c in clinical practice. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
standardization, reference methods, network, HbA1c, diabetes, glycated hemoglobin
in
Clinical Chemistry and Laboratory Medicine
volume
45
issue
8
pages
1077 - 1080
publisher
De Gruyter
external identifiers
  • wos:000249266400026
  • scopus:34548792393
ISSN
1434-6621
DOI
10.1515/CCLM.2007.246
language
English
LU publication?
yes
id
4e5e11dd-0000-4d3b-aea5-5ee105364bae (old id 689557)
date added to LUP
2016-04-01 12:13:03
date last changed
2022-05-06 23:23:44
@article{4e5e11dd-0000-4d3b-aea5-5ee105364bae,
  abstract     = {{The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes. There are at least 30 different laboratory assays commercially available to measure the proportion of HbA1c in blood. In 1995 the IFCC established a Working Group (IFCC WG-HbA1c) to achieve international standardization of HbA1c measurement. The main achievements can be summarized as follows: a) a reference measurement procedure has been established with purified primary calibrators; b) a network of reference laboratories has been developed worldwide; and c) work has begun on implementation of traceability to the IFCC reference system. The IFCC WG-HbA1c recognizes the recommendation of the IFCC-IUPAC Committee on Nomenclature, Properties and Units that the analyte measured by the IFCC reference measurement procedure has been defined as beta N1-deoxyfructosyl-hemoglobin and that the recommended measurement units are mmol/mol. The IFCC WG-HbA1c recommends maintaining the use of the name HbA1c in clinical practice.}},
  author       = {{Mosca, Andrea and Goodall, Ian and Hoshino, Tadao and Jeppsson, Jan-Olof and John, W. Garry and Little, Randie R. and Miedema, Kor and Myers, Gary L. and Reinauer, Hans and Sacks, David B. and Weykamp, Cas W.}},
  issn         = {{1434-6621}},
  keywords     = {{standardization; reference methods; network; HbA1c; diabetes; glycated hemoglobin}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1077--1080}},
  publisher    = {{De Gruyter}},
  series       = {{Clinical Chemistry and Laboratory Medicine}},
  title        = {{Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group}},
  url          = {{http://dx.doi.org/10.1515/CCLM.2007.246}},
  doi          = {{10.1515/CCLM.2007.246}},
  volume       = {{45}},
  year         = {{2007}},
}