Diagnostic challenges in patients with reninomas and extrarenal renin-producing tumours
(2024) In Clinical Endocrinology- Abstract
Renin-secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work-up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin-producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work-up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose-positron emission tomography-CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/690a4f66-2651-4c5a-ab79-d8b506020ed8
- author
- Fabian, Botond ; Ragnarsson, Oskar ; Prazic, Aleksandar LU ; Rydén, Mikael ; Volpe, Cristina and Lindgren, Ola LU
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- in press
- subject
- keywords
- aldosterone, extrarenal renin-production, juxtaglomerular cell tumour, renal vein catheterisation, renin, reninoma, secondary hypertension
- in
- Clinical Endocrinology
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:38696530
- scopus:85192174029
- ISSN
- 0300-0664
- DOI
- 10.1111/cen.15069
- language
- English
- LU publication?
- yes
- id
- 690a4f66-2651-4c5a-ab79-d8b506020ed8
- date added to LUP
- 2024-05-14 15:34:00
- date last changed
- 2024-06-25 20:04:32
@article{690a4f66-2651-4c5a-ab79-d8b506020ed8, abstract = {{<p>Renin-secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work-up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin-producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work-up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose-positron emission tomography-CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.</p>}}, author = {{Fabian, Botond and Ragnarsson, Oskar and Prazic, Aleksandar and Rydén, Mikael and Volpe, Cristina and Lindgren, Ola}}, issn = {{0300-0664}}, keywords = {{aldosterone; extrarenal renin-production; juxtaglomerular cell tumour; renal vein catheterisation; renin; reninoma; secondary hypertension}}, language = {{eng}}, publisher = {{Wiley-Blackwell}}, series = {{Clinical Endocrinology}}, title = {{Diagnostic challenges in patients with reninomas and extrarenal renin-producing tumours}}, url = {{http://dx.doi.org/10.1111/cen.15069}}, doi = {{10.1111/cen.15069}}, year = {{2024}}, }