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Risk of Appendiceal Malignancy in Conservatively Treated Acute Appendicitis

Ramadan, Shaima LU orcid ; Olsson, Åsa and Buchwald, Pamela LU (2022) In Diseases of the Colon and Rectum 65(5). p.56-56
Abstract
Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear.
Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA.
Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts.
Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA.... (More)
Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear.
Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA.
Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts.
Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA. Median time of follow-up was 45 months. The recurrence rate was lower after uncomplicated AA (13.8%) than for complicated AA (22.2%; p= 0.049). During follow-up 52 (21.8%) of patients with complicated AA underwent appendectomy. Appendiceal malignancies were found in 12 (5%) patients with previous complicated vs no appendiceal malignancies after uncomplicated AA (p= 0.001). Limitations: This study was limited by its retrospective design, the high rate of excluded patients and the variation of follow-up time from index admission to data collection.
Conclusions/Discussion: The relatively low incidence of appendiceal malignancies in this study does not support routine interval appendectomy in patients after complicated AA. Evidence regarding follow-up after conservatively treated AA is scarce and needs to be evaluated according to standardised protocols. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diseases of the Colon and Rectum
volume
65
issue
5
article number
eP116
pages
56 - 56
publisher
Springer
external identifiers
  • pmid:35394944
  • scopus:85128079930
ISSN
0012-3706
DOI
10.1097/DCR.0000000000002459
language
English
LU publication?
yes
id
6922bb60-8488-4794-b832-1788e6fdd8c8
date added to LUP
2022-10-15 21:55:10
date last changed
2022-12-14 04:02:47
@misc{6922bb60-8488-4794-b832-1788e6fdd8c8,
  abstract     = {{Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear. <br/>Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA. <br/>Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts. <br/>Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA. Median time of follow-up was 45 months. The recurrence rate was lower after uncomplicated AA (13.8%) than for complicated AA (22.2%; p= 0.049). During follow-up 52 (21.8%) of patients with complicated AA underwent appendectomy. Appendiceal malignancies were found in 12 (5%) patients with previous complicated vs no appendiceal malignancies after uncomplicated AA (p= 0.001). Limitations: This study was limited by its retrospective design, the high rate of excluded patients and the variation of follow-up time from index admission to data collection. <br/>Conclusions/Discussion: The relatively low incidence of appendiceal malignancies in this study does not support routine interval appendectomy in patients after complicated AA. Evidence regarding follow-up after conservatively treated AA is scarce and needs to be evaluated according to standardised protocols.}},
  author       = {{Ramadan, Shaima and Olsson, Åsa and Buchwald, Pamela}},
  issn         = {{0012-3706}},
  language     = {{eng}},
  month        = {{05}},
  note         = {{Conference Abstract}},
  number       = {{5}},
  pages        = {{56--56}},
  publisher    = {{Springer}},
  series       = {{Diseases of the Colon and Rectum}},
  title        = {{Risk of Appendiceal Malignancy in Conservatively Treated Acute Appendicitis}},
  url          = {{http://dx.doi.org/10.1097/DCR.0000000000002459}},
  doi          = {{10.1097/DCR.0000000000002459}},
  volume       = {{65}},
  year         = {{2022}},
}