Risk of Appendiceal Malignancy in Conservatively Treated Acute Appendicitis
(2022) In Diseases of the Colon and Rectum 65(5). p.56-56- Abstract
- Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear.
Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA.
Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts.
Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA.... (More) - Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear.
Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA.
Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts.
Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA. Median time of follow-up was 45 months. The recurrence rate was lower after uncomplicated AA (13.8%) than for complicated AA (22.2%; p= 0.049). During follow-up 52 (21.8%) of patients with complicated AA underwent appendectomy. Appendiceal malignancies were found in 12 (5%) patients with previous complicated vs no appendiceal malignancies after uncomplicated AA (p= 0.001). Limitations: This study was limited by its retrospective design, the high rate of excluded patients and the variation of follow-up time from index admission to data collection.
Conclusions/Discussion: The relatively low incidence of appendiceal malignancies in this study does not support routine interval appendectomy in patients after complicated AA. Evidence regarding follow-up after conservatively treated AA is scarce and needs to be evaluated according to standardised protocols. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/6922bb60-8488-4794-b832-1788e6fdd8c8
- author
- Ramadan, Shaima LU ; Olsson, Åsa and Buchwald, Pamela LU
- organization
- publishing date
- 2022-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diseases of the Colon and Rectum
- volume
- 65
- issue
- 5
- article number
- eP116
- pages
- 56 - 56
- publisher
- Springer
- external identifiers
-
- pmid:35394944
- scopus:85128079930
- ISSN
- 0012-3706
- DOI
- 10.1097/DCR.0000000000002459
- language
- English
- LU publication?
- yes
- id
- 6922bb60-8488-4794-b832-1788e6fdd8c8
- date added to LUP
- 2022-10-15 21:55:10
- date last changed
- 2022-12-14 04:02:47
@misc{6922bb60-8488-4794-b832-1788e6fdd8c8, abstract = {{Purpose/Background: Appendectomy is the standard treatment of acute appendicitis (AA) but conservative treatment has gained success. The need for follow-up after conservatively treated AA is unclear. <br/>Hypothesis/Aim: This study evaluates follow-up, recurrence and appendiceal malignancy in conservatively treated AA. <br/>Methods/Interventions: This retrospective study included patients with conservatively treated AA at Skåne University Hospital, Sweden during 2012-2019. Information on patient demographics at index admission and data on follow-up, recurrences and later appendectomies were retrieved from medical charts. <br/>Results/Outcome(s): The study cohort included 391 patients, 152 with uncomplicated and 259 with complicated AA. Median time of follow-up was 45 months. The recurrence rate was lower after uncomplicated AA (13.8%) than for complicated AA (22.2%; p= 0.049). During follow-up 52 (21.8%) of patients with complicated AA underwent appendectomy. Appendiceal malignancies were found in 12 (5%) patients with previous complicated vs no appendiceal malignancies after uncomplicated AA (p= 0.001). Limitations: This study was limited by its retrospective design, the high rate of excluded patients and the variation of follow-up time from index admission to data collection. <br/>Conclusions/Discussion: The relatively low incidence of appendiceal malignancies in this study does not support routine interval appendectomy in patients after complicated AA. Evidence regarding follow-up after conservatively treated AA is scarce and needs to be evaluated according to standardised protocols.}}, author = {{Ramadan, Shaima and Olsson, Åsa and Buchwald, Pamela}}, issn = {{0012-3706}}, language = {{eng}}, month = {{05}}, note = {{Conference Abstract}}, number = {{5}}, pages = {{56--56}}, publisher = {{Springer}}, series = {{Diseases of the Colon and Rectum}}, title = {{Risk of Appendiceal Malignancy in Conservatively Treated Acute Appendicitis}}, url = {{http://dx.doi.org/10.1097/DCR.0000000000002459}}, doi = {{10.1097/DCR.0000000000002459}}, volume = {{65}}, year = {{2022}}, }