Asymmetric ring-opening of epoxides catalyzed by metal–salen complexes
(2020) In Catalysts 10(6).- Abstract
The asymmetric ring-opening of epoxides is an important reaction in organic synthesis, since it allows for the enantioselective installation of two vicinal functional groups with specific stereochemistry within one step from a highly available starting material. An effective class of catalysts for the asymmetric ring-opening of epoxides is metal–salen complexes. This review summarizes the development of metal–salen catalyzed enantioselective desymmetrization of meso-epoxides and kinetic resolution of epoxides with various nucleophiles, including the design and application of both homogeneous- and heterogeneous epoxide-opening catalysts as well as multi-metallic covalent and supramolecular catalytic systems.
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https://lup.lub.lu.se/record/695ae940-ef35-496e-ba5a-111be2f2dfd1
- author
- Lidskog, Anna LU ; Li, Yutang LU and Wärnmark, Kenneth LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Asymmetric catalysis, Epoxide, Kinetic resolution, Ring-opening, Salen complexes
- in
- Catalysts
- volume
- 10
- issue
- 6
- article number
- 705
- publisher
- MDPI AG
- external identifiers
-
- scopus:85089116461
- ISSN
- 2073-4344
- DOI
- 10.3390/catal10060705
- language
- English
- LU publication?
- yes
- id
- 695ae940-ef35-496e-ba5a-111be2f2dfd1
- date added to LUP
- 2020-08-18 13:16:48
- date last changed
- 2023-11-20 09:26:23
@article{695ae940-ef35-496e-ba5a-111be2f2dfd1, abstract = {{<p>The asymmetric ring-opening of epoxides is an important reaction in organic synthesis, since it allows for the enantioselective installation of two vicinal functional groups with specific stereochemistry within one step from a highly available starting material. An effective class of catalysts for the asymmetric ring-opening of epoxides is metal–salen complexes. This review summarizes the development of metal–salen catalyzed enantioselective desymmetrization of meso-epoxides and kinetic resolution of epoxides with various nucleophiles, including the design and application of both homogeneous- and heterogeneous epoxide-opening catalysts as well as multi-metallic covalent and supramolecular catalytic systems.</p>}}, author = {{Lidskog, Anna and Li, Yutang and Wärnmark, Kenneth}}, issn = {{2073-4344}}, keywords = {{Asymmetric catalysis; Epoxide; Kinetic resolution; Ring-opening; Salen complexes}}, language = {{eng}}, number = {{6}}, publisher = {{MDPI AG}}, series = {{Catalysts}}, title = {{Asymmetric ring-opening of epoxides catalyzed by metal–salen complexes}}, url = {{http://dx.doi.org/10.3390/catal10060705}}, doi = {{10.3390/catal10060705}}, volume = {{10}}, year = {{2020}}, }