Swelling properties of cross-linked DNA gels.
(2010) In Advances in Colloid and Interface Science 158. p.21-31- Abstract
- This work represents our contribution to the field of physical chemistry of DNA gels, and concerns the synthesis and study of novel chemically cross-linked DNA gels. The use of covalent DNA gels is a very promising way to study DNA-cosolute interactions, as well as the dynamic behaviour of DNA and cationic compacting agents, like lipids, surfactants and polycations. Manipulating DNA in new ways, like DNA networks, allows a better understanding and characterization of DNA-cosolute complexes at the molecular level, and also allows us to follow the assembly structures of these complexes. The use of responsive polymer gels for targeted delivery of toxic and/or labile drugs has, during the past few years, shown to be a promising concept. The... (More)
- This work represents our contribution to the field of physical chemistry of DNA gels, and concerns the synthesis and study of novel chemically cross-linked DNA gels. The use of covalent DNA gels is a very promising way to study DNA-cosolute interactions, as well as the dynamic behaviour of DNA and cationic compacting agents, like lipids, surfactants and polycations. Manipulating DNA in new ways, like DNA networks, allows a better understanding and characterization of DNA-cosolute complexes at the molecular level, and also allows us to follow the assembly structures of these complexes. The use of responsive polymer gels for targeted delivery of toxic and/or labile drugs has, during the past few years, shown to be a promising concept. The features found in the proposed system would find applications in a broader field of gel/drug interaction, for the development of controlled release and targeted delivery devices. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1512180
- author
- Costa, Diana LU ; Miguel, M Graça and Lindman, Björn LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Advances in Colloid and Interface Science
- volume
- 158
- pages
- 21 - 31
- publisher
- Elsevier
- external identifiers
-
- wos:000279194700004
- pmid:19896108
- scopus:77956408418
- pmid:19896108
- ISSN
- 1873-3727
- DOI
- 10.1016/j.cis.2009.10.002
- language
- English
- LU publication?
- yes
- id
- 69ef6049-f4f9-4bc1-8fc8-cecf2eb2e00e (old id 1512180)
- alternative location
- http://www.sciencedirect.com/science/article/B6V5F-4XG3SDB-1/2/9c1ae9c74cffd3ea920e4d61f3e3eb59
- date added to LUP
- 2016-04-01 10:51:22
- date last changed
- 2025-10-14 11:09:46
@article{69ef6049-f4f9-4bc1-8fc8-cecf2eb2e00e,
abstract = {{This work represents our contribution to the field of physical chemistry of DNA gels, and concerns the synthesis and study of novel chemically cross-linked DNA gels. The use of covalent DNA gels is a very promising way to study DNA-cosolute interactions, as well as the dynamic behaviour of DNA and cationic compacting agents, like lipids, surfactants and polycations. Manipulating DNA in new ways, like DNA networks, allows a better understanding and characterization of DNA-cosolute complexes at the molecular level, and also allows us to follow the assembly structures of these complexes. The use of responsive polymer gels for targeted delivery of toxic and/or labile drugs has, during the past few years, shown to be a promising concept. The features found in the proposed system would find applications in a broader field of gel/drug interaction, for the development of controlled release and targeted delivery devices.}},
author = {{Costa, Diana and Miguel, M Graça and Lindman, Björn}},
issn = {{1873-3727}},
language = {{eng}},
pages = {{21--31}},
publisher = {{Elsevier}},
series = {{Advances in Colloid and Interface Science}},
title = {{Swelling properties of cross-linked DNA gels.}},
url = {{http://dx.doi.org/10.1016/j.cis.2009.10.002}},
doi = {{10.1016/j.cis.2009.10.002}},
volume = {{158}},
year = {{2010}},
}