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Capacitive biosensors for ultra-sensitive assays

Mattiasson, Bo LU and Hedström, Martin LU (2016) In Trac. Trends in Analytical Chemistry 79. p.233-238
Abstract

Capacitive binding assays have long been considered highly sensitive. The underlying method in such assays includes sending short potential pulses and then registering the current. However, with the introduction of current pulses and registration of potential responses, the stability improved significantly, leading to assays of extreme sensitivities. The new assaying technology has been applied in a range of affinity binding assays, from immunoassays via DNA base pairing to the use of molecularly imprinted polymers (MIPs). Overall, very good sensitivities have been recorded, and the MIPs exhibit high stability and reusability.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Affinity biosensor, Capacitive transduction, Electropolymerization, Gold surface, Microcontact imprinting, MIP, Ultra-sensitive
in
Trac. Trends in Analytical Chemistry
volume
79
pages
6 pages
publisher
Elsevier
external identifiers
  • Scopus:84964661180
  • WOS:000376703900023
ISSN
0165-9936
DOI
10.1016/j.trac.2015.10.016
language
English
LU publication?
yes
id
6a4d4612-3846-42e2-ab6c-a20b82339782
date added to LUP
2016-07-08 13:17:25
date last changed
2016-12-14 11:43:08
@article{6a4d4612-3846-42e2-ab6c-a20b82339782,
  abstract     = {<p>Capacitive binding assays have long been considered highly sensitive. The underlying method in such assays includes sending short potential pulses and then registering the current. However, with the introduction of current pulses and registration of potential responses, the stability improved significantly, leading to assays of extreme sensitivities. The new assaying technology has been applied in a range of affinity binding assays, from immunoassays via DNA base pairing to the use of molecularly imprinted polymers (MIPs). Overall, very good sensitivities have been recorded, and the MIPs exhibit high stability and reusability.</p>},
  author       = {Mattiasson, Bo and Hedström, Martin},
  issn         = {0165-9936},
  keyword      = {Affinity biosensor,Capacitive transduction,Electropolymerization,Gold surface,Microcontact imprinting,MIP,Ultra-sensitive},
  language     = {eng},
  month        = {05},
  pages        = {233--238},
  publisher    = {Elsevier},
  series       = {Trac. Trends in Analytical Chemistry},
  title        = {Capacitive biosensors for ultra-sensitive assays},
  url          = {http://dx.doi.org/10.1016/j.trac.2015.10.016},
  volume       = {79},
  year         = {2016},
}