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The Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA) : Methodology, Cohort Demographics and Initial Results

Hill, Mattias LU orcid ; Jörgensen, Sophie LU ; Engström, Gunnar LU ; Persson, Margaretha LU orcid and Lexell, Jan LU (2020) In American Journal of Physical Medicine and Rehabilitation 99(6). p.522-531
Abstract

OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).

DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.

RESULTS: Of 38 potential... (More)

OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).

DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.

RESULTS: Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 years, mean time since injury 28 years). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease (CVD). Asthma was previously diagnosed in only 8% and none had chronic obstructive pulmonary disease.

CONCLUSION: The risk for CVD in people with severe high-level SCI is a major clinical concern. Forthcoming studies in SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Physical Medicine and Rehabilitation
volume
99
issue
6
pages
522 - 531
publisher
Lippincott Williams & Wilkins
external identifiers
  • scopus:85085264518
  • pmid:32167960
ISSN
1537-7385
DOI
10.1097/PHM.0000000000001365
language
English
LU publication?
yes
id
6a89a84d-6b46-439d-b0d9-301e04076f3e
date added to LUP
2020-03-19 10:11:11
date last changed
2024-04-03 04:39:31
@article{6a89a84d-6b46-439d-b0d9-301e04076f3e,
  abstract     = {{<p>OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).</p><p>DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.</p><p>RESULTS: Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 years, mean time since injury 28 years). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease (CVD). Asthma was previously diagnosed in only 8% and none had chronic obstructive pulmonary disease.</p><p>CONCLUSION: The risk for CVD in people with severe high-level SCI is a major clinical concern. Forthcoming studies in SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.</p>}},
  author       = {{Hill, Mattias and Jörgensen, Sophie and Engström, Gunnar and Persson, Margaretha and Lexell, Jan}},
  issn         = {{1537-7385}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{6}},
  pages        = {{522--531}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{American Journal of Physical Medicine and Rehabilitation}},
  title        = {{The Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA) : Methodology, Cohort Demographics and Initial Results}},
  url          = {{http://dx.doi.org/10.1097/PHM.0000000000001365}},
  doi          = {{10.1097/PHM.0000000000001365}},
  volume       = {{99}},
  year         = {{2020}},
}