The Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA) : Methodology, Cohort Demographics and Initial Results
(2020) In American Journal of Physical Medicine and Rehabilitation 99(6). p.522-531- Abstract
OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).
DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.
RESULTS: Of 38 potential... (More)
OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).
DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.
RESULTS: Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 years, mean time since injury 28 years). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease (CVD). Asthma was previously diagnosed in only 8% and none had chronic obstructive pulmonary disease.
CONCLUSION: The risk for CVD in people with severe high-level SCI is a major clinical concern. Forthcoming studies in SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.
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- author
- Hill, Mattias LU ; Jörgensen, Sophie LU ; Engström, Gunnar LU ; Persson, Margaretha LU and Lexell, Jan LU
- organization
- publishing date
- 2020-03-11
- type
- Contribution to journal
- publication status
- published
- subject
- in
- American Journal of Physical Medicine and Rehabilitation
- volume
- 99
- issue
- 6
- pages
- 522 - 531
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- scopus:85085264518
- pmid:32167960
- ISSN
- 1537-7385
- DOI
- 10.1097/PHM.0000000000001365
- language
- English
- LU publication?
- yes
- id
- 6a89a84d-6b46-439d-b0d9-301e04076f3e
- date added to LUP
- 2020-03-19 10:11:11
- date last changed
- 2024-04-03 04:39:31
@article{6a89a84d-6b46-439d-b0d9-301e04076f3e, abstract = {{<p>OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).</p><p>DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.</p><p>RESULTS: Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 years, mean time since injury 28 years). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease (CVD). Asthma was previously diagnosed in only 8% and none had chronic obstructive pulmonary disease.</p><p>CONCLUSION: The risk for CVD in people with severe high-level SCI is a major clinical concern. Forthcoming studies in SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.</p>}}, author = {{Hill, Mattias and Jörgensen, Sophie and Engström, Gunnar and Persson, Margaretha and Lexell, Jan}}, issn = {{1537-7385}}, language = {{eng}}, month = {{03}}, number = {{6}}, pages = {{522--531}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{American Journal of Physical Medicine and Rehabilitation}}, title = {{The Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA) : Methodology, Cohort Demographics and Initial Results}}, url = {{http://dx.doi.org/10.1097/PHM.0000000000001365}}, doi = {{10.1097/PHM.0000000000001365}}, volume = {{99}}, year = {{2020}}, }