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Reduced thalamic activity in ADHD under ABR forward masking conditions

Källstrand, Johan ; Niklasson, Katalin LU ; Lindvall, Magnus LU and Claesdotter-Knutsson, Emma LU (2022) In Applied Neuropsychology: Child
Abstract

Attention-deficit hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder characterized by symptoms of inattention, overactivity, and/or impulsiveness. The prevalence of ADHD varies in different settings and there have been voices raised to call for more objective measures in order to avoid over- and underdiagnosing of ADHD. Auditory Brainstem Response (ABR) is a method where click shaped sounds evoke potentials that are recorder from electrodes on the skull of a patient. The aim of this study was to explore possible alterations in the ABR of 29 patients with ADHD compared to 39 healthy controls. We used a forward masked sound. We found differences in ABR that correspond to the thalamic area. The thalamus seems to... (More)

Attention-deficit hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder characterized by symptoms of inattention, overactivity, and/or impulsiveness. The prevalence of ADHD varies in different settings and there have been voices raised to call for more objective measures in order to avoid over- and underdiagnosing of ADHD. Auditory Brainstem Response (ABR) is a method where click shaped sounds evoke potentials that are recorder from electrodes on the skull of a patient. The aim of this study was to explore possible alterations in the ABR of 29 patients with ADHD compared to 39 healthy controls. We used a forward masked sound. We found differences in ABR that correspond to the thalamic area. The thalamus seems to play an active role in regulation of activity level in ADHD. More research is needed to draw any further conclusions on using ABR as an objective measurement to detect ADHD.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
in press
subject
keywords
ABR, ADHD, child and adolescent psychiatry, thalamus
in
Applied Neuropsychology: Child
publisher
Taylor & Francis
external identifiers
  • pmid:36524942
  • scopus:85144217717
ISSN
2162-2965
DOI
10.1080/21622965.2022.2155520
language
English
LU publication?
yes
id
6aaaca02-ae37-4e11-9ff6-e556e122243b
date added to LUP
2023-01-23 15:38:42
date last changed
2024-04-16 12:44:22
@article{6aaaca02-ae37-4e11-9ff6-e556e122243b,
  abstract     = {{<p>Attention-deficit hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder characterized by symptoms of inattention, overactivity, and/or impulsiveness. The prevalence of ADHD varies in different settings and there have been voices raised to call for more objective measures in order to avoid over- and underdiagnosing of ADHD. Auditory Brainstem Response (ABR) is a method where click shaped sounds evoke potentials that are recorder from electrodes on the skull of a patient. The aim of this study was to explore possible alterations in the ABR of 29 patients with ADHD compared to 39 healthy controls. We used a forward masked sound. We found differences in ABR that correspond to the thalamic area. The thalamus seems to play an active role in regulation of activity level in ADHD. More research is needed to draw any further conclusions on using ABR as an objective measurement to detect ADHD.</p>}},
  author       = {{Källstrand, Johan and Niklasson, Katalin and Lindvall, Magnus and Claesdotter-Knutsson, Emma}},
  issn         = {{2162-2965}},
  keywords     = {{ABR; ADHD; child and adolescent psychiatry; thalamus}},
  language     = {{eng}},
  publisher    = {{Taylor & Francis}},
  series       = {{Applied Neuropsychology: Child}},
  title        = {{Reduced thalamic activity in ADHD under ABR forward masking conditions}},
  url          = {{http://dx.doi.org/10.1080/21622965.2022.2155520}},
  doi          = {{10.1080/21622965.2022.2155520}},
  year         = {{2022}},
}