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Atrial Impulses at the Atrioventricular Node: Arrival versus Conduction during Atrial Fibrillation

Iozzia, L.; Garoldi, G.; Sandberg, Frida LU ; Corino, Valentina D A; Mainardi, Luca T. and Sörnmo, Leif LU (2015) 16th Nordic-Baltic Conference on Biomedical Engineering (NBC) / 10th MTD Joint Conference In 16th Nordic-Baltic Conference on Biomedical Engineering p.100-103
Abstract
The atrioventricular (AV) node plays a central role during atrial fibrillation (AF).We have recently proposed a statistical AV node model defined by parameters characterizing the arrival rate of atrial impulses, the probability of an impulse choosing the slower of the two AV nodal pathways, the refractory periods of the pathways, and the prolongation of refractory periods. All model parameters are estimated from the RR series using maximum likelihood estimation, except for the mean arrival rate of atrial impulses which is estimated by the AF frequency derived from the f-waves. The aim of this study is to assess the relationship between the probability γ of an atrial impulse to arrive at the slow pathway with the probability α (used in the... (More)
The atrioventricular (AV) node plays a central role during atrial fibrillation (AF).We have recently proposed a statistical AV node model defined by parameters characterizing the arrival rate of atrial impulses, the probability of an impulse choosing the slower of the two AV nodal pathways, the refractory periods of the pathways, and the prolongation of refractory periods. All model parameters are estimated from the RR series using maximum likelihood estimation, except for the mean arrival rate of atrial impulses which is estimated by the AF frequency derived from the f-waves. The aim of this study is to assess the relationship between the probability γ of an atrial impulse to arrive at the slow pathway with the probability α (used in the model) of an impulse to pass through that pathway. A theoretical equation was derived to relate α with γ and viceversa, highlighting the dependence on both refractory periods and their prolongation. Results based on simulations show that the equation was correct, with an average absolute error of 0.0034 ± 0.0008. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
in
16th Nordic-Baltic Conference on Biomedical Engineering
pages
100 - 103
publisher
Springer
conference name
16th Nordic-Baltic Conference on Biomedical Engineering (NBC) / 10th MTD Joint Conference
external identifiers
  • scopus:84910614746
ISBN
978-3-319-12966-2
978-3-319-12967-9
DOI
10.1007/978-3-319-12967-9_27
language
English
LU publication?
yes
id
6abe1109-8f74-40a3-9f0d-4537bc3d5823
date added to LUP
2017-08-09 15:22:51
date last changed
2017-08-13 05:11:14
@inproceedings{6abe1109-8f74-40a3-9f0d-4537bc3d5823,
  abstract     = {The atrioventricular (AV) node plays a central role during atrial fibrillation (AF).We have recently proposed a statistical AV node model defined by parameters characterizing the arrival rate of atrial impulses, the probability of an impulse choosing the slower of the two AV nodal pathways, the refractory periods of the pathways, and the prolongation of refractory periods. All model parameters are estimated from the RR series using maximum likelihood estimation, except for the mean arrival rate of atrial impulses which is estimated by the AF frequency derived from the f-waves. The aim of this study is to assess the relationship between the probability γ of an atrial impulse to arrive at the slow pathway with the probability α (used in the model) of an impulse to pass through that pathway. A theoretical equation was derived to relate α with γ and viceversa, highlighting the dependence on both refractory periods and their prolongation. Results based on simulations show that the equation was correct, with an average absolute error of 0.0034 ± 0.0008.},
  author       = {Iozzia, L. and Garoldi, G. and Sandberg, Frida and Corino, Valentina D A and Mainardi, Luca T. and Sörnmo, Leif},
  booktitle    = {16th Nordic-Baltic Conference on Biomedical Engineering},
  isbn         = {978-3-319-12966-2},
  language     = {eng},
  pages        = {100--103},
  publisher    = {Springer},
  title        = {Atrial Impulses at the Atrioventricular Node: Arrival versus Conduction during Atrial Fibrillation},
  url          = {http://dx.doi.org/10.1007/978-3-319-12967-9_27},
  year         = {2015},
}