Melting mapping in nanochannels
Reisner, Walter W. ; Flyvbjerg, Henrik and Tegenfeldt, Jonas O. LU
(2008)
12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
p.1516-1518
- Abstract
We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/6b02dea2-ceab-47e3-8ed0-ebc37b5106aa
- author
- Reisner, Walter W.
; Flyvbjerg, Henrik
and Tegenfeldt, Jonas O.
LU
- organization
- publishing date
- 2008-01-01
- type
- Contribution to conference
- publication status
- published
- keywords
- DNA, Genomics, Melting, Nanofluidics
- pages
- 3 pages
- conference name
- 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
- conference location
- San Diego, CA, United States
- conference dates
- 2008-10-12 - 2008-10-16
- external identifiers
-
- scopus:84902504260
- language
- English
- LU publication?
- yes
- id
- 6b02dea2-ceab-47e3-8ed0-ebc37b5106aa
- date added to LUP
- 2018-10-20 10:33:30
- date last changed
- 2022-01-31 06:19:35
@misc{6b02dea2-ceab-47e3-8ed0-ebc37b5106aa,
abstract = {{<p>We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.</p>}},
author = {{Reisner, Walter W. and Flyvbjerg, Henrik and Tegenfeldt, Jonas O.}},
keywords = {{DNA; Genomics; Melting; Nanofluidics}},
language = {{eng}},
month = {{01}},
pages = {{1516--1518}},
title = {{Melting mapping in nanochannels}},
year = {{2008}},
}