Evaluation of different coatings of the tibial tray in uncemented total knee arthroplasty. A randomized controlled trial with 5 years follow-up with RSA and DEXA
(2021) In Knee 29. p.208-215- Abstract
Background: Regenerex® is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with... (More)
Background: Regenerex® is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with measurements of migration. In total 55 patients attended the 5-year follow-up. Results: One patient died and four were reoperated during the 60-months period; none due to aseptic loosening. All reoperations were in the VR-group. The mean (range) 60-months MTPM was 1.4 mm (0.5–3.7) for the VP-group and 1.8 mm (0.4–4.9) for the VR-group (p = 0.8). The 24 to 60-months mean (range) MTPM was −0.3 mm (−5 to 1.24) in the VP-group and 0.2 mm (−0.4 to 3.5) in the VR-group (p = 0.8). Conclusion: We did not find any statistically significant differences between the VP- and VR-group and both groups show recognizable migration. We will continue to follow the groups for years to come.
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- author
- Dyreborg, Karen ; Winther, Nikolaj ; Lind, Thomas ; Flivik, Gunnar LU and Mørk Petersen, Michael
- organization
- publishing date
- 2021-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Dual energy X-ray absorptiometry, Primary, Radiostereometric analysis, TKA, Total knee arthroplasty, Uncemented
- in
- Knee
- volume
- 29
- pages
- 8 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:85101585547
- pmid:33647748
- ISSN
- 0968-0160
- DOI
- 10.1016/j.knee.2021.02.002
- language
- English
- LU publication?
- yes
- id
- 6c21a0a7-ced5-479a-95df-9c420ae7ce76
- date added to LUP
- 2021-12-23 08:26:13
- date last changed
- 2025-03-10 00:32:05
@article{6c21a0a7-ced5-479a-95df-9c420ae7ce76,
abstract = {{<p>Background: Regenerex® is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with measurements of migration. In total 55 patients attended the 5-year follow-up. Results: One patient died and four were reoperated during the 60-months period; none due to aseptic loosening. All reoperations were in the VR-group. The mean (range) 60-months MTPM was 1.4 mm (0.5–3.7) for the VP-group and 1.8 mm (0.4–4.9) for the VR-group (p = 0.8). The 24 to 60-months mean (range) MTPM was −0.3 mm (−5 to 1.24) in the VP-group and 0.2 mm (−0.4 to 3.5) in the VR-group (p = 0.8). Conclusion: We did not find any statistically significant differences between the VP- and VR-group and both groups show recognizable migration. We will continue to follow the groups for years to come.</p>}},
author = {{Dyreborg, Karen and Winther, Nikolaj and Lind, Thomas and Flivik, Gunnar and Mørk Petersen, Michael}},
issn = {{0968-0160}},
keywords = {{Dual energy X-ray absorptiometry; Primary; Radiostereometric analysis; TKA; Total knee arthroplasty; Uncemented}},
language = {{eng}},
pages = {{208--215}},
publisher = {{Elsevier}},
series = {{Knee}},
title = {{Evaluation of different coatings of the tibial tray in uncemented total knee arthroplasty. A randomized controlled trial with 5 years follow-up with RSA and DEXA}},
url = {{http://dx.doi.org/10.1016/j.knee.2021.02.002}},
doi = {{10.1016/j.knee.2021.02.002}},
volume = {{29}},
year = {{2021}},
}