Primary diphtheria immunisation of adolescents and adults with low-dose vaccine, a survey of historic evidence from the literature
(2023) In Acta Paediatrica, International Journal of Paediatrics 112(2). p.242-245- Abstract
The Public Health Agency of Sweden carried out a literature review on diphtheria vaccinations for seronegative people above 6 years of age with an uncertain vaccine history. The aim was to harmonise national Swedish recommendations with the current World Health Organization recommendations. There was no firm conclusion about dosage. Some low-dose vaccines used in the past had suboptimal potency, while others evoked adequate levels of antitoxin after three primary doses. We concluded that low-dose diphtheria vaccines that have been approved by a national medical products agency can be used for primary vaccination against diphtheria for individuals above 6 years of age.
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https://lup.lub.lu.se/record/6dd34bdf-713c-40fd-a684-4388c5677ae5
- author
- Kahn, Fredrik LU ; Lepp, Tiia and Storsaeter, Jann
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diphtheria, low dosage, primary, toxoid, vaccination
- in
- Acta Paediatrica, International Journal of Paediatrics
- volume
- 112
- issue
- 2
- pages
- 4 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:36333877
- scopus:85143361472
- ISSN
- 0803-5253
- DOI
- 10.1111/apa.16589
- language
- English
- LU publication?
- yes
- id
- 6dd34bdf-713c-40fd-a684-4388c5677ae5
- date added to LUP
- 2023-01-30 12:48:00
- date last changed
- 2024-06-09 12:15:32
@article{6dd34bdf-713c-40fd-a684-4388c5677ae5,
abstract = {{<p>The Public Health Agency of Sweden carried out a literature review on diphtheria vaccinations for seronegative people above 6 years of age with an uncertain vaccine history. The aim was to harmonise national Swedish recommendations with the current World Health Organization recommendations. There was no firm conclusion about dosage. Some low-dose vaccines used in the past had suboptimal potency, while others evoked adequate levels of antitoxin after three primary doses. We concluded that low-dose diphtheria vaccines that have been approved by a national medical products agency can be used for primary vaccination against diphtheria for individuals above 6 years of age.</p>}},
author = {{Kahn, Fredrik and Lepp, Tiia and Storsaeter, Jann}},
issn = {{0803-5253}},
keywords = {{diphtheria; low dosage; primary; toxoid; vaccination}},
language = {{eng}},
number = {{2}},
pages = {{242--245}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Paediatrica, International Journal of Paediatrics}},
title = {{Primary diphtheria immunisation of adolescents and adults with low-dose vaccine, a survey of historic evidence from the literature}},
url = {{http://dx.doi.org/10.1111/apa.16589}},
doi = {{10.1111/apa.16589}},
volume = {{112}},
year = {{2023}},
}