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Type 1 diabetes as a risk factor for stroke in men and women aged 15-49 : a nationwide study from Sweden

Sundquist, K LU and Li, X LU (2006) In Diabetic medicine : a journal of the British Diabetic Association 23(11). p.7-1261
Abstract

AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.

METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic... (More)

AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.

METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic complications.

RESULTS: The overall SIRs for premature stroke in men and women with hospital admission for Type 1 diabetes were 17.94 [95% confidence interval (CI) 12.87, 24.36] and 26.11 (95% CI 18.81, 35.32), respectively. Men and women with diabetic nephropathy had the highest significant SIRs of premature stroke: 48.87 and 73.53, respectively.

CONCLUSIONS: Our data indicate that young to middle-aged individuals with Type 1 diabetes had a considerably higher risk of premature stroke than those without Type 1 diabetes. This underscores the need to implement vigorous interventions in healthcare settings in order to decrease the risk of premature stroke in individuals with Type 1 diabetes.

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author
publishing date
type
Contribution to journal
publication status
published
keywords
Adolescent, Adult, Diabetes Mellitus, Type 1/epidemiology, Diabetic Angiopathies/epidemiology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Risk Factors, Stroke/epidemiology, Sweden/epidemiology
in
Diabetic medicine : a journal of the British Diabetic Association
volume
23
issue
11
pages
7 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:33750194146
  • pmid:17054606
ISSN
0742-3071
DOI
10.1111/j.1464-5491.2006.01959.x
language
English
LU publication?
no
id
6e43adda-876f-4ac8-ab61-fb55876d35f8
date added to LUP
2019-01-30 11:11:25
date last changed
2020-01-13 01:25:13
@article{6e43adda-876f-4ac8-ab61-fb55876d35f8,
  abstract     = {<p>AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.</p><p>METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic complications.</p><p>RESULTS: The overall SIRs for premature stroke in men and women with hospital admission for Type 1 diabetes were 17.94 [95% confidence interval (CI) 12.87, 24.36] and 26.11 (95% CI 18.81, 35.32), respectively. Men and women with diabetic nephropathy had the highest significant SIRs of premature stroke: 48.87 and 73.53, respectively.</p><p>CONCLUSIONS: Our data indicate that young to middle-aged individuals with Type 1 diabetes had a considerably higher risk of premature stroke than those without Type 1 diabetes. This underscores the need to implement vigorous interventions in healthcare settings in order to decrease the risk of premature stroke in individuals with Type 1 diabetes.</p>},
  author       = {Sundquist, K and Li, X},
  issn         = {0742-3071},
  language     = {eng},
  number       = {11},
  pages        = {7--1261},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetic medicine : a journal of the British Diabetic Association},
  title        = {Type 1 diabetes as a risk factor for stroke in men and women aged 15-49 : a nationwide study from Sweden},
  url          = {http://dx.doi.org/10.1111/j.1464-5491.2006.01959.x},
  doi          = {10.1111/j.1464-5491.2006.01959.x},
  volume       = {23},
  year         = {2006},
}