Type 1 diabetes as a risk factor for stroke in men and women aged 15-49 : a nationwide study from Sweden
(2006) In Diabetic Medicine: A journal of the British Diabetic Association 23(11). p.7-1261- Abstract
AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.
METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic... (More)
AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.
METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic complications.
RESULTS: The overall SIRs for premature stroke in men and women with hospital admission for Type 1 diabetes were 17.94 [95% confidence interval (CI) 12.87, 24.36] and 26.11 (95% CI 18.81, 35.32), respectively. Men and women with diabetic nephropathy had the highest significant SIRs of premature stroke: 48.87 and 73.53, respectively.
CONCLUSIONS: Our data indicate that young to middle-aged individuals with Type 1 diabetes had a considerably higher risk of premature stroke than those without Type 1 diabetes. This underscores the need to implement vigorous interventions in healthcare settings in order to decrease the risk of premature stroke in individuals with Type 1 diabetes.
(Less)
- author
- Sundquist, K LU and Li, X LU
- publishing date
- 2006-11
- type
- Contribution to journal
- publication status
- published
- keywords
- Adolescent, Adult, Diabetes Mellitus, Type 1/epidemiology, Diabetic Angiopathies/epidemiology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Risk Factors, Stroke/epidemiology, Sweden/epidemiology
- in
- Diabetic Medicine: A journal of the British Diabetic Association
- volume
- 23
- issue
- 11
- pages
- 7 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:33750194146
- pmid:17054606
- ISSN
- 0742-3071
- DOI
- 10.1111/j.1464-5491.2006.01959.x
- language
- English
- LU publication?
- no
- id
- 6e43adda-876f-4ac8-ab61-fb55876d35f8
- date added to LUP
- 2019-01-30 11:11:25
- date last changed
- 2024-06-11 03:46:29
@article{6e43adda-876f-4ac8-ab61-fb55876d35f8, abstract = {{<p>AIMS: The main objective was to determine premature stroke risk in men and women in Sweden with previous hospital admission for Type 1 diabetes or without previous hospital admission.</p><p>METHODS: All individuals in Sweden aged 15-34 years at first hospital admission for Type 1 diabetes and aged 15-49 years at first hospital admission for stroke during the study period (1987-2001) were identified. Standardized incidence ratios (SIRs) were calculated to compare premature stroke risk between individuals admitted to hospital with Type 1 diabetes and individuals without hospital admission, after controlling for age, time period, occupation and geographical region. SIRs were also calculated for individuals with diabetic complications.</p><p>RESULTS: The overall SIRs for premature stroke in men and women with hospital admission for Type 1 diabetes were 17.94 [95% confidence interval (CI) 12.87, 24.36] and 26.11 (95% CI 18.81, 35.32), respectively. Men and women with diabetic nephropathy had the highest significant SIRs of premature stroke: 48.87 and 73.53, respectively.</p><p>CONCLUSIONS: Our data indicate that young to middle-aged individuals with Type 1 diabetes had a considerably higher risk of premature stroke than those without Type 1 diabetes. This underscores the need to implement vigorous interventions in healthcare settings in order to decrease the risk of premature stroke in individuals with Type 1 diabetes.</p>}}, author = {{Sundquist, K and Li, X}}, issn = {{0742-3071}}, keywords = {{Adolescent; Adult; Diabetes Mellitus, Type 1/epidemiology; Diabetic Angiopathies/epidemiology; Female; Follow-Up Studies; Humans; Male; Middle Aged; Risk Factors; Stroke/epidemiology; Sweden/epidemiology}}, language = {{eng}}, number = {{11}}, pages = {{7--1261}}, publisher = {{Wiley-Blackwell}}, series = {{Diabetic Medicine: A journal of the British Diabetic Association}}, title = {{Type 1 diabetes as a risk factor for stroke in men and women aged 15-49 : a nationwide study from Sweden}}, url = {{http://dx.doi.org/10.1111/j.1464-5491.2006.01959.x}}, doi = {{10.1111/j.1464-5491.2006.01959.x}}, volume = {{23}}, year = {{2006}}, }