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Generation of Transplantable Striatal Projection Neurons from Human ESCs.

Parmar, Malin LU orcid and Björklund, Anders LU orcid (2012) In Cell Stem Cell 10(4). p.349-350
Abstract
In this issue of Cell Stem Cell, Ma et al. (2012) report a differentiation protocol for generating striatal projection neurons from human embryonic stem cells with high efficiency. The cells survive transplantation, reconnect striatal circuitry, and restore motor function in a mouse model of striatal neurodegeneration that mimics the central pathohology of Huntington's disease.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cell Stem Cell
volume
10
issue
4
pages
349 - 350
publisher
Cell Press
external identifiers
  • wos:000303079400002
  • pmid:22482498
  • scopus:84859544526
  • pmid:22482498
ISSN
1934-5909
DOI
10.1016/j.stem.2012.03.004
language
English
LU publication?
yes
id
6f227f4e-c25a-437b-b1f5-c027a7699c5b (old id 2519740)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22482498?dopt=Abstract
date added to LUP
2016-04-04 08:33:04
date last changed
2022-01-29 03:32:15
@article{6f227f4e-c25a-437b-b1f5-c027a7699c5b,
  abstract     = {{In this issue of Cell Stem Cell, Ma et al. (2012) report a differentiation protocol for generating striatal projection neurons from human embryonic stem cells with high efficiency. The cells survive transplantation, reconnect striatal circuitry, and restore motor function in a mouse model of striatal neurodegeneration that mimics the central pathohology of Huntington's disease.}},
  author       = {{Parmar, Malin and Björklund, Anders}},
  issn         = {{1934-5909}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{349--350}},
  publisher    = {{Cell Press}},
  series       = {{Cell Stem Cell}},
  title        = {{Generation of Transplantable Striatal Projection Neurons from Human ESCs.}},
  url          = {{http://dx.doi.org/10.1016/j.stem.2012.03.004}},
  doi          = {{10.1016/j.stem.2012.03.004}},
  volume       = {{10}},
  year         = {{2012}},
}