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Passive smoking and childhood asthma. Urinary cotinine levels in children with asthma and in referents

Willers, Stefan LU ; Svenonius, E and Skarping, Gunnar LU (1991) In Allergy 46(5). p.330-334
Abstract
Passive exposure to tobacco smoke was assessed in children with asthma (age 3-15) and in referents. There was statistically significantly (P less than 0.0005) higher excretion of the nicotine metabolite, cotinine, in the urine of 49 children with asthma (geometric mean 10 ng/ml) compared with 77 referents (4.8 ng/ml). Maternal smoking was statistically significantly more prevalent among the asthmatics than among the referents (relative risk = RR = 2.6, 95% C1 = 1.2-5.3). In conclusion, the exposure to environmental tobacco smoke in asthmatic children was higher than among healthy children, indicating that passive smoking may be a predisposing and/or aggravating factor for childhood asthma.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cotinine, childhood asthma, involuntary, passive smoking, predisposing factor
in
Allergy
volume
46
issue
5
pages
330 - 334
publisher
Wiley-Blackwell
external identifiers
  • pmid:1928656
  • scopus:0025728042
ISSN
1398-9995
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Occupational and Environmental Medicine (013078001), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
id
6f8d15f5-3536-47fa-a1ff-1f296d093cbb (old id 1106045)
date added to LUP
2016-04-01 16:29:06
date last changed
2021-09-12 05:03:24
@article{6f8d15f5-3536-47fa-a1ff-1f296d093cbb,
  abstract     = {{Passive exposure to tobacco smoke was assessed in children with asthma (age 3-15) and in referents. There was statistically significantly (P less than 0.0005) higher excretion of the nicotine metabolite, cotinine, in the urine of 49 children with asthma (geometric mean 10 ng/ml) compared with 77 referents (4.8 ng/ml). Maternal smoking was statistically significantly more prevalent among the asthmatics than among the referents (relative risk = RR = 2.6, 95% C1 = 1.2-5.3). In conclusion, the exposure to environmental tobacco smoke in asthmatic children was higher than among healthy children, indicating that passive smoking may be a predisposing and/or aggravating factor for childhood asthma.}},
  author       = {{Willers, Stefan and Svenonius, E and Skarping, Gunnar}},
  issn         = {{1398-9995}},
  keywords     = {{cotinine; childhood asthma; involuntary; passive smoking; predisposing factor}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{330--334}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Allergy}},
  title        = {{Passive smoking and childhood asthma. Urinary cotinine levels in children with asthma and in referents}},
  volume       = {{46}},
  year         = {{1991}},
}