Panel 8 : Report on Recent Advances in Molecular and Cellular Biochemistry
(2017) In Otolaryngology - Head and Neck Surgery 156(4_suppl). p.106-113- Abstract
Objectives: To update the medical literature on recent cellular and molecular advances in otitis media disease models with a principal focus on developments in the past 5 years. We also aim to explain recent translational advances in cellular and molecular biology that have influenced our understanding and management of otitis media. Data Sources: PubMed-indexed peer-reviewed articles. Review Methods: A comprehensive review of the literature was conducted with the term otitis media and the following search terms: molecular biology, cell biology, innate immunity, oxidative stress, mucins, molecular diagnostics. Included articles were published in the English language from January 1, 2010, to July 31, 2015. Implications for Practice: The... (More)
Objectives: To update the medical literature on recent cellular and molecular advances in otitis media disease models with a principal focus on developments in the past 5 years. We also aim to explain recent translational advances in cellular and molecular biology that have influenced our understanding and management of otitis media. Data Sources: PubMed-indexed peer-reviewed articles. Review Methods: A comprehensive review of the literature was conducted with the term otitis media and the following search terms: molecular biology, cell biology, innate immunity, oxidative stress, mucins, molecular diagnostics. Included articles were published in the English language from January 1, 2010, to July 31, 2015. Implications for Practice: The molecular understanding of otitis media disease progression has rapidly advanced over the last 5 years. The roles of inflammation, mucins, and cell signaling mechanisms have been elucidated and defined. Advances in the field provide a plethora of opportunities for innovative molecular targeting in the development of novel therapeutic strategies for otitis media.
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- author
- Preciado, Diego ; Granath, Anna ; Lin, Jizhen ; Val, Stéphanie ; Kurabi, Arwa ; Johnston, Nikki ; Vijayasekaran, Shyan ; Valdez, Tulio ; Depireux, Didier and Hermansson, Ann LU
- organization
- publishing date
- 2017-04-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- biofilms, cell biology, innate immunity, molecular biology, molecular diagnostics, mucins, NETs, optical coherence tomography, otitis media, oxidative stress, Toll-like receptors
- in
- Otolaryngology - Head and Neck Surgery
- volume
- 156
- issue
- 4_suppl
- pages
- 106 - 113
- publisher
- Mosby-Elsevier
- external identifiers
-
- scopus:85018984822
- pmid:28372528
- wos:000402853500008
- ISSN
- 0194-5998
- DOI
- 10.1177/0194599816658290
- language
- English
- LU publication?
- yes
- id
- 706ba7e2-877f-4f63-a5e9-21d35dcd62a4
- date added to LUP
- 2017-06-14 10:04:25
- date last changed
- 2024-07-22 23:10:47
@article{706ba7e2-877f-4f63-a5e9-21d35dcd62a4, abstract = {{<p>Objectives: To update the medical literature on recent cellular and molecular advances in otitis media disease models with a principal focus on developments in the past 5 years. We also aim to explain recent translational advances in cellular and molecular biology that have influenced our understanding and management of otitis media. Data Sources: PubMed-indexed peer-reviewed articles. Review Methods: A comprehensive review of the literature was conducted with the term otitis media and the following search terms: molecular biology, cell biology, innate immunity, oxidative stress, mucins, molecular diagnostics. Included articles were published in the English language from January 1, 2010, to July 31, 2015. Implications for Practice: The molecular understanding of otitis media disease progression has rapidly advanced over the last 5 years. The roles of inflammation, mucins, and cell signaling mechanisms have been elucidated and defined. Advances in the field provide a plethora of opportunities for innovative molecular targeting in the development of novel therapeutic strategies for otitis media.</p>}}, author = {{Preciado, Diego and Granath, Anna and Lin, Jizhen and Val, Stéphanie and Kurabi, Arwa and Johnston, Nikki and Vijayasekaran, Shyan and Valdez, Tulio and Depireux, Didier and Hermansson, Ann}}, issn = {{0194-5998}}, keywords = {{biofilms; cell biology; innate immunity; molecular biology; molecular diagnostics; mucins; NETs; optical coherence tomography; otitis media; oxidative stress; Toll-like receptors}}, language = {{eng}}, month = {{04}}, number = {{4_suppl}}, pages = {{106--113}}, publisher = {{Mosby-Elsevier}}, series = {{Otolaryngology - Head and Neck Surgery}}, title = {{Panel 8 : Report on Recent Advances in Molecular and Cellular Biochemistry}}, url = {{http://dx.doi.org/10.1177/0194599816658290}}, doi = {{10.1177/0194599816658290}}, volume = {{156}}, year = {{2017}}, }