Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy
(2019) In Journal of Biophotonics 12(6).- Abstract
An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads... (More)
An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads to over-prescription of antibiotics and alarming increase in bacterial resistance development. More accurate diagnostic methods are highly desirable. Diffuse reflectance spectroscopy is a non-invasive quantitative spectroscopic technique that enables to objectively quantify changes in the hemoglobin content of the tympanic membrane related to inflammation. If an infection is present, the ventilatory function of the Eustachian tube is frequently impaired and the middle-ear cavity will be filled with fluid. GASMAS, a non-invasive detection method, can non-invasively determine if gas is replaced by fluid in the middle-ear cavity.
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- author
- Hu, Lingna ; Li, Wansha ; Lin, Huiying ; Li, Ying ; Zhang, Hao ; Svanberg, Katarina LU and Svanberg, Sune LU
- organization
- publishing date
- 2019-02-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diagnostics, diffuse reflectance spectroscopy, ear infection, GASMAS, otitis media, otoscope
- in
- Journal of Biophotonics
- volume
- 12
- issue
- 6
- article number
- e201800305
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85062340251
- pmid:30719866
- ISSN
- 1864-063X
- DOI
- 10.1002/jbio.201800305
- language
- English
- LU publication?
- yes
- id
- 70a179da-24e4-487b-a9c5-0c7db37d7767
- date added to LUP
- 2019-03-14 10:39:58
- date last changed
- 2024-12-11 01:49:45
@article{70a179da-24e4-487b-a9c5-0c7db37d7767,
abstract = {{<p>An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads to over-prescription of antibiotics and alarming increase in bacterial resistance development. More accurate diagnostic methods are highly desirable. Diffuse reflectance spectroscopy is a non-invasive quantitative spectroscopic technique that enables to objectively quantify changes in the hemoglobin content of the tympanic membrane related to inflammation. If an infection is present, the ventilatory function of the Eustachian tube is frequently impaired and the middle-ear cavity will be filled with fluid. GASMAS, a non-invasive detection method, can non-invasively determine if gas is replaced by fluid in the middle-ear cavity.</p>}},
author = {{Hu, Lingna and Li, Wansha and Lin, Huiying and Li, Ying and Zhang, Hao and Svanberg, Katarina and Svanberg, Sune}},
issn = {{1864-063X}},
keywords = {{diagnostics; diffuse reflectance spectroscopy; ear infection; GASMAS; otitis media; otoscope}},
language = {{eng}},
month = {{02}},
number = {{6}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Biophotonics}},
title = {{Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy}},
url = {{http://dx.doi.org/10.1002/jbio.201800305}},
doi = {{10.1002/jbio.201800305}},
volume = {{12}},
year = {{2019}},
}