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Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy

Hu, Lingna ; Li, Wansha ; Lin, Huiying ; Li, Ying ; Zhang, Hao ; Svanberg, Katarina LU and Svanberg, Sune LU (2019) In Journal of Biophotonics 12(6).
Abstract

An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads... (More)

An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads to over-prescription of antibiotics and alarming increase in bacterial resistance development. More accurate diagnostic methods are highly desirable. Diffuse reflectance spectroscopy is a non-invasive quantitative spectroscopic technique that enables to objectively quantify changes in the hemoglobin content of the tympanic membrane related to inflammation. If an infection is present, the ventilatory function of the Eustachian tube is frequently impaired and the middle-ear cavity will be filled with fluid. GASMAS, a non-invasive detection method, can non-invasively determine if gas is replaced by fluid in the middle-ear cavity.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diagnostics, diffuse reflectance spectroscopy, ear infection, GASMAS, otitis media, otoscope
in
Journal of Biophotonics
volume
12
issue
6
article number
e201800305
publisher
John Wiley & Sons
external identifiers
  • pmid:30719866
  • scopus:85062340251
ISSN
1864-063X
DOI
10.1002/jbio.201800305
language
English
LU publication?
yes
id
70a179da-24e4-487b-a9c5-0c7db37d7767
date added to LUP
2019-03-14 10:39:58
date last changed
2020-01-22 07:29:53
@article{70a179da-24e4-487b-a9c5-0c7db37d7767,
  abstract     = {<p>An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Inaccurate diagnosis related to similar symptoms, and the difficulty for small children to describe the condition experienced, frequently leads to over-prescription of antibiotics and alarming increase in bacterial resistance development. More accurate diagnostic methods are highly desirable. Diffuse reflectance spectroscopy is a non-invasive quantitative spectroscopic technique that enables to objectively quantify changes in the hemoglobin content of the tympanic membrane related to inflammation. If an infection is present, the ventilatory function of the Eustachian tube is frequently impaired and the middle-ear cavity will be filled with fluid. GASMAS, a non-invasive detection method, can non-invasively determine if gas is replaced by fluid in the middle-ear cavity.</p>},
  author       = {Hu, Lingna and Li, Wansha and Lin, Huiying and Li, Ying and Zhang, Hao and Svanberg, Katarina and Svanberg, Sune},
  issn         = {1864-063X},
  language     = {eng},
  month        = {02},
  number       = {6},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Biophotonics},
  title        = {Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy},
  url          = {http://dx.doi.org/10.1002/jbio.201800305},
  doi          = {10.1002/jbio.201800305},
  volume       = {12},
  year         = {2019},
}