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Postprandial increase in serum creatinine in renal transplant recipients

Sterner, Gunnar LU ; Wroblewski, Marek and Rosén, Ulf (1992) In Transplant International 5(2). p.115-117
Abstract
Daily variation in serum creatinine and the effect of a protein load was studied in 18 patients with renal transplants and in 10 healthy controls. Serum creatinine was analyzed both with a standard Jaffé method and with a specific HPLC technique. Following a protein meal, a 30% increase in serum creatinine levels was noted in both groups, but the rise in absolute terms was more prominent among the transplanted patients. Urinary excretion of creatinine did not increase in the transplanted group, indicating a reduced ability to deal with the surplus creatinine in the protein meal. It is concluded that serum creatinine levels are diet-dependent and that this variation is more pronounced when renal function is reduced. Standardized blood... (More)
Daily variation in serum creatinine and the effect of a protein load was studied in 18 patients with renal transplants and in 10 healthy controls. Serum creatinine was analyzed both with a standard Jaffé method and with a specific HPLC technique. Following a protein meal, a 30% increase in serum creatinine levels was noted in both groups, but the rise in absolute terms was more prominent among the transplanted patients. Urinary excretion of creatinine did not increase in the transplanted group, indicating a reduced ability to deal with the surplus creatinine in the protein meal. It is concluded that serum creatinine levels are diet-dependent and that this variation is more pronounced when renal function is reduced. Standardized blood sampling is important when following serum creatinine in renal transplant recipients from one day to the next. (Less)
Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Transplant International
volume
5
issue
2
pages
115 - 117
publisher
Springer
external identifiers
  • scopus:0026668416
ISSN
1432-2277
DOI
10.1111/j.1432-2277.1992.tb01765.x
language
English
LU publication?
no
id
7195725a-4018-402b-b8f8-efb5703f991b
date added to LUP
2019-10-26 22:40:52
date last changed
2021-01-03 07:50:49
@article{7195725a-4018-402b-b8f8-efb5703f991b,
  abstract     = {{Daily variation in serum creatinine and the effect of a protein load was studied in 18 patients with renal transplants and in 10 healthy controls. Serum creatinine was analyzed both with a standard Jaffé method and with a specific HPLC technique. Following a protein meal, a 30% increase in serum creatinine levels was noted in both groups, but the rise in absolute terms was more prominent among the transplanted patients. Urinary excretion of creatinine did not increase in the transplanted group, indicating a reduced ability to deal with the surplus creatinine in the protein meal. It is concluded that serum creatinine levels are diet-dependent and that this variation is more pronounced when renal function is reduced. Standardized blood sampling is important when following serum creatinine in renal transplant recipients from one day to the next.}},
  author       = {{Sterner, Gunnar and Wroblewski, Marek and Rosén, Ulf}},
  issn         = {{1432-2277}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{115--117}},
  publisher    = {{Springer}},
  series       = {{Transplant International}},
  title        = {{Postprandial increase in serum creatinine in renal transplant recipients}},
  url          = {{http://dx.doi.org/10.1111/j.1432-2277.1992.tb01765.x}},
  doi          = {{10.1111/j.1432-2277.1992.tb01765.x}},
  volume       = {{5}},
  year         = {{1992}},
}