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Outbreak of occupational allergic contact dermatitis from a smartphone screen protector glue

Herreros-Montejano, Francisca ; Mowitz, Martin LU ; Heras-Mendaza, Felipe ; Sanz-Sánchez, Tatiana ; Gatica-Ortega, María Elena ; López-Mateos, Ana ; Valenzuela-Oñate, Cristian ; Faura-Berruga, Cristina ; Zaragoza-Ninet, Violeta and Bruze, Magnus LU , et al. (2022) In Contact Dermatitis 87(1). p.53-61
Abstract

Background: Sensitization to acrylates is a concern in the occupational/environmental dermatology field. Objective: To describe an occupational allergic contact dermatitis (ACD) outbreak from a smartphone screen protector glue. Methods: Thirteen affected workers of a chain store selling phone screen protectors were investigated in five Spanish dermatology departments. The glue datasheet and label were assessed. A chemical analysis of the glue was performed. Based on this, some patients underwent additional testing. Results: All patients (all female, mean age: 25) had severe fingertip dermatitis. The datasheet/label indicated that the glue contained isobornyl acrylate (IBOA), a “photoinitiator” and polyurethane oligomer. The company... (More)

Background: Sensitization to acrylates is a concern in the occupational/environmental dermatology field. Objective: To describe an occupational allergic contact dermatitis (ACD) outbreak from a smartphone screen protector glue. Methods: Thirteen affected workers of a chain store selling phone screen protectors were investigated in five Spanish dermatology departments. The glue datasheet and label were assessed. A chemical analysis of the glue was performed. Based on this, some patients underwent additional testing. Results: All patients (all female, mean age: 25) had severe fingertip dermatitis. The datasheet/label indicated that the glue contained isobornyl acrylate (IBOA), a “photoinitiator” and polyurethane oligomer. The company informed us that the ingredients were polyurethane acrylate, “methacrylate” (unspecified), acrylic acid, hydroxyethyl methacrylate, propylmethoxy siloxane, and photoinitiator 184. Isobornyl acrylate (or IBOA) and N,N-dimethylacrylamide (DMAA) were patch tested in eight and two cases, respectively, with negative results. A chemical analysis revealed 4-acryloylmorpholine (ACMO); isobornyl methacrylate (IBMA), and lauryl acrylate in one glue sample. Seven patients were patch tested with dilutions of the identified substances and six of seven were positive for ACMO 0.5% pet. Conclusion: An outbreak of occupational ACD, likely from ACMO in a glue is described. Further investigations are needed to corroborate the role played by each compound identified in the chemical analyses.

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@article{71b8ba52-74cb-4b25-86cf-33dc95aa9f30,
  abstract     = {{<p>Background: Sensitization to acrylates is a concern in the occupational/environmental dermatology field. Objective: To describe an occupational allergic contact dermatitis (ACD) outbreak from a smartphone screen protector glue. Methods: Thirteen affected workers of a chain store selling phone screen protectors were investigated in five Spanish dermatology departments. The glue datasheet and label were assessed. A chemical analysis of the glue was performed. Based on this, some patients underwent additional testing. Results: All patients (all female, mean age: 25) had severe fingertip dermatitis. The datasheet/label indicated that the glue contained isobornyl acrylate (IBOA), a “photoinitiator” and polyurethane oligomer. The company informed us that the ingredients were polyurethane acrylate, “methacrylate” (unspecified), acrylic acid, hydroxyethyl methacrylate, propylmethoxy siloxane, and photoinitiator 184. Isobornyl acrylate (or IBOA) and N,N-dimethylacrylamide (DMAA) were patch tested in eight and two cases, respectively, with negative results. A chemical analysis revealed 4-acryloylmorpholine (ACMO); isobornyl methacrylate (IBMA), and lauryl acrylate in one glue sample. Seven patients were patch tested with dilutions of the identified substances and six of seven were positive for ACMO 0.5% pet. Conclusion: An outbreak of occupational ACD, likely from ACMO in a glue is described. Further investigations are needed to corroborate the role played by each compound identified in the chemical analyses.</p>}},
  author       = {{Herreros-Montejano, Francisca and Mowitz, Martin and Heras-Mendaza, Felipe and Sanz-Sánchez, Tatiana and Gatica-Ortega, María Elena and López-Mateos, Ana and Valenzuela-Oñate, Cristian and Faura-Berruga, Cristina and Zaragoza-Ninet, Violeta and Bruze, Magnus and Svedman, Cecilia and Pastor-Nieto, María Antonia}},
  issn         = {{0105-1873}},
  keywords     = {{4-acryloylmorpholine; ACMO; acrylates; allergic contact dermatitis; case series; glue; isobornyl acrylate (IBOA); isobornyl methacrylate (IBMA); lauryl acrylate; smartphone}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{53--61}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Outbreak of occupational allergic contact dermatitis from a smartphone screen protector glue}},
  url          = {{http://dx.doi.org/10.1111/cod.14079}},
  doi          = {{10.1111/cod.14079}},
  volume       = {{87}},
  year         = {{2022}},
}