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Isolation of rat major histocompatibility genes expressed in pancreatic β-cells

Kastern, W. H. ; Lernmark, A. LU orcid and Lyngsie, L. (1983) In Acta Biologica et Medica Germanica 41(12). p.1135-1138
Abstract

The probable role of cell surface antigens in the development of juvenile diabetes necessitates a detailed study of the proteins expressed on the surface of pancreatic β-cells. A gene library composed of genes expressed in β-cells was constructed to provide a source of low abundance genes from those cells. Initial studies with this library have led to the isolation of three genes which share nucleotide and amino acid sequence homology with mouse and human class I major histocompatibility antigens.

Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
in
Acta Biologica et Medica Germanica
volume
41
issue
12
pages
4 pages
publisher
Akademie Verlag GMBH
external identifiers
  • scopus:0020628139
  • pmid:6765156
ISSN
0001-5318
language
English
LU publication?
no
id
71e363fc-78fb-46c8-aed4-cf54ca33a2c8
date added to LUP
2019-09-16 12:46:46
date last changed
2024-03-13 08:15:11
@article{71e363fc-78fb-46c8-aed4-cf54ca33a2c8,
  abstract     = {{<p>The probable role of cell surface antigens in the development of juvenile diabetes necessitates a detailed study of the proteins expressed on the surface of pancreatic β-cells. A gene library composed of genes expressed in β-cells was constructed to provide a source of low abundance genes from those cells. Initial studies with this library have led to the isolation of three genes which share nucleotide and amino acid sequence homology with mouse and human class I major histocompatibility antigens.</p>}},
  author       = {{Kastern, W. H. and Lernmark, A. and Lyngsie, L.}},
  issn         = {{0001-5318}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{12}},
  pages        = {{1135--1138}},
  publisher    = {{Akademie Verlag GMBH}},
  series       = {{Acta Biologica et Medica Germanica}},
  title        = {{Isolation of rat major histocompatibility genes expressed in pancreatic β-cells}},
  volume       = {{41}},
  year         = {{1983}},
}