Isolation of rat major histocompatibility genes expressed in pancreatic β-cells
(1983) In Acta Biologica et Medica Germanica 41(12). p.1135-1138- Abstract
The probable role of cell surface antigens in the development of juvenile diabetes necessitates a detailed study of the proteins expressed on the surface of pancreatic β-cells. A gene library composed of genes expressed in β-cells was constructed to provide a source of low abundance genes from those cells. Initial studies with this library have led to the isolation of three genes which share nucleotide and amino acid sequence homology with mouse and human class I major histocompatibility antigens.
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https://lup.lub.lu.se/record/71e363fc-78fb-46c8-aed4-cf54ca33a2c8
- author
- Kastern, W. H. ; Lernmark, A. LU and Lyngsie, L.
- publishing date
- 1983-01-01
- type
- Contribution to journal
- publication status
- published
- in
- Acta Biologica et Medica Germanica
- volume
- 41
- issue
- 12
- pages
- 4 pages
- publisher
- Akademie Verlag GMBH
- external identifiers
-
- pmid:6765156
- scopus:0020628139
- ISSN
- 0001-5318
- language
- English
- LU publication?
- no
- id
- 71e363fc-78fb-46c8-aed4-cf54ca33a2c8
- date added to LUP
- 2019-09-16 12:46:46
- date last changed
- 2024-03-13 08:15:11
@article{71e363fc-78fb-46c8-aed4-cf54ca33a2c8, abstract = {{<p>The probable role of cell surface antigens in the development of juvenile diabetes necessitates a detailed study of the proteins expressed on the surface of pancreatic β-cells. A gene library composed of genes expressed in β-cells was constructed to provide a source of low abundance genes from those cells. Initial studies with this library have led to the isolation of three genes which share nucleotide and amino acid sequence homology with mouse and human class I major histocompatibility antigens.</p>}}, author = {{Kastern, W. H. and Lernmark, A. and Lyngsie, L.}}, issn = {{0001-5318}}, language = {{eng}}, month = {{01}}, number = {{12}}, pages = {{1135--1138}}, publisher = {{Akademie Verlag GMBH}}, series = {{Acta Biologica et Medica Germanica}}, title = {{Isolation of rat major histocompatibility genes expressed in pancreatic β-cells}}, volume = {{41}}, year = {{1983}}, }