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Clinical course in synovial sarcoma : A Scandinavian sarcoma group study of 104 patients

Skytting, Björn T. ; Bauer, Henrik C.F. ; Perfekt, Roland LU ; Huuhtanen, Riika ; Alvegârd, Thor A. LU ; Berlin, Örjan ; Gustafson, Pelle LU ; Klepp, Ragnhild ; Löfvenberg, Richard and Seter, Gunnar , et al. (1999) In Acta Orthopaedica Scandinavica 70(6). p.536-542
Abstract

We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.

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publication status
published
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Acta Orthopaedica Scandinavica
volume
70
issue
6
pages
536 - 542
publisher
Taylor & Francis
external identifiers
  • scopus:6744240530
  • pmid:10665716
ISSN
0001-6470
DOI
10.3109/17453679908997839
language
English
LU publication?
yes
id
724b4d73-23a6-414a-9c14-64a266a4783f
date added to LUP
2019-05-25 07:52:26
date last changed
2019-11-25 09:30:46
@article{724b4d73-23a6-414a-9c14-64a266a4783f,
  abstract     = {<p>We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.</p>},
  author       = {Skytting, Björn T. and Bauer, Henrik C.F. and Perfekt, Roland and Huuhtanen, Riika and Alvegârd, Thor A. and Berlin, Örjan and Gustafson, Pelle and Klepp, Ragnhild and Löfvenberg, Richard and Seter, Gunnar and Trovik, Clement S. and Wahlström, Ola},
  issn         = {0001-6470},
  language     = {eng},
  number       = {6},
  pages        = {536--542},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica Scandinavica},
  title        = {Clinical course in synovial sarcoma : A Scandinavian sarcoma group study of 104 patients},
  url          = {http://dx.doi.org/10.3109/17453679908997839},
  doi          = {10.3109/17453679908997839},
  volume       = {70},
  year         = {1999},
}