Clinical course in synovial sarcoma : A Scandinavian sarcoma group study of 104 patients
(1999) In Acta Orthopaedica Scandinavica 70(6). p.536-542- Abstract
We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.
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- author
- organization
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Orthopaedica Scandinavica
- volume
- 70
- issue
- 6
- pages
- 536 - 542
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:10665716
- scopus:6744240530
- ISSN
- 0001-6470
- DOI
- 10.3109/17453679908997839
- language
- English
- LU publication?
- yes
- id
- 724b4d73-23a6-414a-9c14-64a266a4783f
- date added to LUP
- 2019-05-25 07:52:26
- date last changed
- 2024-07-09 15:37:09
@article{724b4d73-23a6-414a-9c14-64a266a4783f, abstract = {{<p>We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.</p>}}, author = {{Skytting, Björn T. and Bauer, Henrik C.F. and Perfekt, Roland and Huuhtanen, Riika and Alvegârd, Thor A. and Berlin, Örjan and Gustafson, Pelle and Klepp, Ragnhild and Löfvenberg, Richard and Seter, Gunnar and Trovik, Clement S. and Wahlström, Ola}}, issn = {{0001-6470}}, language = {{eng}}, number = {{6}}, pages = {{536--542}}, publisher = {{Taylor & Francis}}, series = {{Acta Orthopaedica Scandinavica}}, title = {{Clinical course in synovial sarcoma : A Scandinavian sarcoma group study of 104 patients}}, url = {{http://dx.doi.org/10.3109/17453679908997839}}, doi = {{10.3109/17453679908997839}}, volume = {{70}}, year = {{1999}}, }