Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.
(2014) In Journal of Hypertension 32(2). p.294-299- Abstract
- We have previously shown that genetic variance in NEDD4L, a regulating protein of a sodium channel in the distal nephron, has been associated with marginally higher blood pressure and enhanced salt sensitivity. Here, we tested if the genetic NEDD4L variation previously associated with salt sensitivity is related to population blood pressure, incidence of cardiovascular disease (CVD) and mortality.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4178856
- author
- Dahlberg, Jonas LU ; Sjögren, Marketa LU ; Hedblad, Bo LU ; Engström, Gunnar LU and Melander, Olle LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Hypertension
- volume
- 32
- issue
- 2
- pages
- 294 - 299
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:24284497
- wos:000330876000014
- scopus:84892959334
- pmid:24284497
- ISSN
- 1473-5598
- DOI
- 10.1097/HJH.0000000000000044
- language
- English
- LU publication?
- yes
- id
- 729d9598-f06d-4501-ad09-842b1b31b45d (old id 4178856)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24284497?dopt=Abstract
- date added to LUP
- 2016-04-01 10:00:33
- date last changed
- 2024-01-06 05:27:45
@article{729d9598-f06d-4501-ad09-842b1b31b45d, abstract = {{We have previously shown that genetic variance in NEDD4L, a regulating protein of a sodium channel in the distal nephron, has been associated with marginally higher blood pressure and enhanced salt sensitivity. Here, we tested if the genetic NEDD4L variation previously associated with salt sensitivity is related to population blood pressure, incidence of cardiovascular disease (CVD) and mortality.}}, author = {{Dahlberg, Jonas and Sjögren, Marketa and Hedblad, Bo and Engström, Gunnar and Melander, Olle}}, issn = {{1473-5598}}, language = {{eng}}, number = {{2}}, pages = {{294--299}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Journal of Hypertension}}, title = {{Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.}}, url = {{http://dx.doi.org/10.1097/HJH.0000000000000044}}, doi = {{10.1097/HJH.0000000000000044}}, volume = {{32}}, year = {{2014}}, }