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Bipolar Patients' Quality of Life in Mixed States: A Preliminary Qualitative Study

Mortensen, Gitte Lee; Vinberg, Maj; Mortensen, Steen Lee; Jorgensen, Martin Balslev and Eberhard, Jonas LU (2015) In Psychopathology 48(3). p.192-201
Abstract
Background: Approximately 20% of patients with bipolar disorder experience mixed states. Mixed states are associated with more comorbidity, poorer treatment response and prognosis, increased relapse rate, and decreased functioning. This study aimed to produce in-depth knowledge about bipolar patients' quality of life (QoL) and functioning related to mixed states. Sampling and Methods: This study used qualitative research methods. A semi-structured interview guide based on a literature study was applied in interviews with 6 remitted bipolar I patients having experienced mixed states. A medical anthropological approach was applied to analyse the data. Results: Participants described mixed states as worse than other bipolar disorder states... (More)
Background: Approximately 20% of patients with bipolar disorder experience mixed states. Mixed states are associated with more comorbidity, poorer treatment response and prognosis, increased relapse rate, and decreased functioning. This study aimed to produce in-depth knowledge about bipolar patients' quality of life (QoL) and functioning related to mixed states. Sampling and Methods: This study used qualitative research methods. A semi-structured interview guide based on a literature study was applied in interviews with 6 remitted bipolar I patients having experienced mixed states. A medical anthropological approach was applied to analyse the data. Results: Participants described mixed states as worse than other bipolar disorder states and their residual symptoms were prolonged. Mixed states affected the functioning of patients in key life domains such as self-esteem, family, love and social life, physical well-being, and working capability. Conclusions: Mixed states may severely affect the QoL and functioning of bipolar patients. Our results indicate that improving these should be a main goal of patient treatment. With an aim of adequately identifying and treating mixed states, our findings highlight the need for knowledge about this particularly severe expression of bipolar disorder. These results should be confirmed in a larger sample of patients with varying socioeconomic status. (C) 2015 S. Karger AG, Basel (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bipolar disease, Mixed states, Mixed episodes, Quality of life, Functioning, Qualitative research, Mania with depressive symptoms, Dysphoric mania
in
Psychopathology
volume
48
issue
3
pages
192 - 201
publisher
Karger
external identifiers
  • wos:000355070100007
  • scopus:84929964470
ISSN
0254-4962
DOI
10.1159/000381479
language
English
LU publication?
yes
id
9558d619-76a1-4c55-b79a-69f84922d514 (old id 7411034)
date added to LUP
2015-07-03 07:02:50
date last changed
2017-08-08 12:44:52
@article{9558d619-76a1-4c55-b79a-69f84922d514,
  abstract     = {Background: Approximately 20% of patients with bipolar disorder experience mixed states. Mixed states are associated with more comorbidity, poorer treatment response and prognosis, increased relapse rate, and decreased functioning. This study aimed to produce in-depth knowledge about bipolar patients' quality of life (QoL) and functioning related to mixed states. Sampling and Methods: This study used qualitative research methods. A semi-structured interview guide based on a literature study was applied in interviews with 6 remitted bipolar I patients having experienced mixed states. A medical anthropological approach was applied to analyse the data. Results: Participants described mixed states as worse than other bipolar disorder states and their residual symptoms were prolonged. Mixed states affected the functioning of patients in key life domains such as self-esteem, family, love and social life, physical well-being, and working capability. Conclusions: Mixed states may severely affect the QoL and functioning of bipolar patients. Our results indicate that improving these should be a main goal of patient treatment. With an aim of adequately identifying and treating mixed states, our findings highlight the need for knowledge about this particularly severe expression of bipolar disorder. These results should be confirmed in a larger sample of patients with varying socioeconomic status. (C) 2015 S. Karger AG, Basel},
  author       = {Mortensen, Gitte Lee and Vinberg, Maj and Mortensen, Steen Lee and Jorgensen, Martin Balslev and Eberhard, Jonas},
  issn         = {0254-4962},
  keyword      = {Bipolar disease,Mixed states,Mixed episodes,Quality of life,Functioning,Qualitative research,Mania with depressive symptoms,Dysphoric mania},
  language     = {eng},
  number       = {3},
  pages        = {192--201},
  publisher    = {Karger},
  series       = {Psychopathology},
  title        = {Bipolar Patients' Quality of Life in Mixed States: A Preliminary Qualitative Study},
  url          = {http://dx.doi.org/10.1159/000381479},
  volume       = {48},
  year         = {2015},
}