Impact of fasting glucose on electrocardiographic left ventricular hypertrophy in an elderly general population
(2015) In Blood Pressure 24(3). p.164-173- Abstract
- Objective. To evaluate relationships between fasting plasma glucose (FPG), other cardiovascular risk markers and left ventricular hypertrophy (LVH) as detected by electrocardiography. Methods. Subjects were selected randomly from groups defi ned by FPG. Traditional risk markers were assessed. LVH was defi ned by either Cornell voltage -duration product (CP) or Sokolow -Lyon voltage combination (SL), and univariate and multivariable regressions were performed in search of explanatory factors for the presence of LVH and the values of CP and SL. Results. Of the 1759 subjects included, 1007 had a history of cardiovascular disease and/or medical treatment, while 752 subjects appeared to be healthy. We found an independent association between... (More)
- Objective. To evaluate relationships between fasting plasma glucose (FPG), other cardiovascular risk markers and left ventricular hypertrophy (LVH) as detected by electrocardiography. Methods. Subjects were selected randomly from groups defi ned by FPG. Traditional risk markers were assessed. LVH was defi ned by either Cornell voltage -duration product (CP) or Sokolow -Lyon voltage combination (SL), and univariate and multivariable regressions were performed in search of explanatory factors for the presence of LVH and the values of CP and SL. Results. Of the 1759 subjects included, 1007 had a history of cardiovascular disease and/or medical treatment, while 752 subjects appeared to be healthy. We found an independent association between FPG and LVH (odds ratio 1.152, p = 0.042] as well as continuous CP (beta = 0.126, p = 0.007) in healthy men. As expected, we found an association between systolic blood pressure and LVH (odds ratio 1.020, p < 0.001) among healthy subjects, but only in subjects with FPG < 6 mmol/l (p = 0.04 for interaction). Conclusions. We found an independent association between FPG and LVH in healthy men, and no potentiating effect by FPG on the impact of hypertension. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7424980
- author
- Diederichsen, Soren Z. ; Pareek, Manan ; Nielsen, Mette L. ; D'Souza, Maria ; Leosdottir, Margret ; Nilsson, Peter LU and Olsen, Michael H.
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aged, diabetes mellitus, electrocardiography, glucose, hypertension, left ventricular hypertrophy
- in
- Blood Pressure
- volume
- 24
- issue
- 3
- pages
- 164 - 173
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000354191800005
- scopus:84928990166
- pmid:25881496
- ISSN
- 0803-7051
- DOI
- 10.3109/08037051.2015.1030892
- language
- English
- LU publication?
- yes
- id
- b898d88c-5a97-47c2-afe5-96ebffc7bf11 (old id 7424980)
- date added to LUP
- 2016-04-01 10:02:42
- date last changed
- 2022-01-25 19:11:52
@article{b898d88c-5a97-47c2-afe5-96ebffc7bf11,
abstract = {{Objective. To evaluate relationships between fasting plasma glucose (FPG), other cardiovascular risk markers and left ventricular hypertrophy (LVH) as detected by electrocardiography. Methods. Subjects were selected randomly from groups defi ned by FPG. Traditional risk markers were assessed. LVH was defi ned by either Cornell voltage -duration product (CP) or Sokolow -Lyon voltage combination (SL), and univariate and multivariable regressions were performed in search of explanatory factors for the presence of LVH and the values of CP and SL. Results. Of the 1759 subjects included, 1007 had a history of cardiovascular disease and/or medical treatment, while 752 subjects appeared to be healthy. We found an independent association between FPG and LVH (odds ratio 1.152, p = 0.042] as well as continuous CP (beta = 0.126, p = 0.007) in healthy men. As expected, we found an association between systolic blood pressure and LVH (odds ratio 1.020, p < 0.001) among healthy subjects, but only in subjects with FPG < 6 mmol/l (p = 0.04 for interaction). Conclusions. We found an independent association between FPG and LVH in healthy men, and no potentiating effect by FPG on the impact of hypertension.}},
author = {{Diederichsen, Soren Z. and Pareek, Manan and Nielsen, Mette L. and D'Souza, Maria and Leosdottir, Margret and Nilsson, Peter and Olsen, Michael H.}},
issn = {{0803-7051}},
keywords = {{Aged; diabetes mellitus; electrocardiography; glucose; hypertension; left ventricular hypertrophy}},
language = {{eng}},
number = {{3}},
pages = {{164--173}},
publisher = {{Taylor & Francis}},
series = {{Blood Pressure}},
title = {{Impact of fasting glucose on electrocardiographic left ventricular hypertrophy in an elderly general population}},
url = {{http://dx.doi.org/10.3109/08037051.2015.1030892}},
doi = {{10.3109/08037051.2015.1030892}},
volume = {{24}},
year = {{2015}},
}