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Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.

Bersani, Francesco Saverio; Morley, Claire; Lindqvist, Daniel LU ; Epel, Elissa S; Picard, Martin; Yehuda, Rachel; Flory, Janine; Bierer, Linda M; Makotkine, Iouri and Abu-Amara, Duna, et al. (2016) In Progress in Neuro-Psychopharmacology and Biological Psychiatry 64(Jun 25). p.10-17
Abstract
Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.
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Contribution to journal
publication status
published
subject
in
Progress in Neuro-Psychopharmacology and Biological Psychiatry
volume
64
issue
Jun 25
pages
10 - 17
publisher
Elsevier
external identifiers
  • pmid:26120081
  • wos:000360921600002
  • scopus:84936818683
ISSN
0278-5846
DOI
10.1016/j.pnpbp.2015.06.012
language
English
LU publication?
yes
id
648964d1-e70c-4041-adee-2300f8d79a55 (old id 7477447)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26120081?dopt=Abstract
date added to LUP
2015-07-11 10:18:26
date last changed
2017-11-12 03:15:10
@article{648964d1-e70c-4041-adee-2300f8d79a55,
  abstract     = {Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.},
  author       = {Bersani, Francesco Saverio and Morley, Claire and Lindqvist, Daniel and Epel, Elissa S and Picard, Martin and Yehuda, Rachel and Flory, Janine and Bierer, Linda M and Makotkine, Iouri and Abu-Amara, Duna and Coy, Michelle and Reus, Victor I and Lin, Jue and Blackburn, Elizabeth H and Marmar, Charles and Wolkowitz, Owen M and Mellon, Synthia H},
  issn         = {0278-5846},
  language     = {eng},
  number       = {Jun 25},
  pages        = {10--17},
  publisher    = {Elsevier},
  series       = {Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  title        = {Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.},
  url          = {http://dx.doi.org/10.1016/j.pnpbp.2015.06.012},
  volume       = {64},
  year         = {2016},
}