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Autoantibody profiling can predict primary Sjögren's syndrome years before diagnosis and identify those with early onset and severe disease course.

Theander, Elke LU ; Jonsson, Roland; Sjöström, Bitte; Brokstad, Karl; Olsson, Peterx LU and Henriksson, Gunnel LU (2015) In Arthritis & rheumatology (Hoboken, N.J.) 67(9). p.2427-2436
Abstract
Autoantibodies are highly characteristic of primary Sjögren's syndrome (pSS) and represent important tools to study its pathogenesis. Nonetheless, thus far no systematic investigations have assessed the presence of autoantibodies before diagnosis. We analysed how early and in which order these appear, how predictive they are for pSS and if they identify disease subsets.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Arthritis & rheumatology (Hoboken, N.J.)
volume
67
issue
9
pages
2427 - 2436
publisher
Wiley-Blackwell
external identifiers
  • pmid:26109563
  • wos:000360379500017
  • scopus:84940118840
ISSN
2326-5205
DOI
10.1002/art.39214
language
English
LU publication?
yes
id
c81a4398-5eb2-456a-b9ac-0b1ff87d9140 (old id 7477982)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26109563?dopt=Abstract
date added to LUP
2015-07-10 22:26:21
date last changed
2017-11-19 03:23:57
@article{c81a4398-5eb2-456a-b9ac-0b1ff87d9140,
  abstract     = {Autoantibodies are highly characteristic of primary Sjögren's syndrome (pSS) and represent important tools to study its pathogenesis. Nonetheless, thus far no systematic investigations have assessed the presence of autoantibodies before diagnosis. We analysed how early and in which order these appear, how predictive they are for pSS and if they identify disease subsets.},
  author       = {Theander, Elke and Jonsson, Roland and Sjöström, Bitte and Brokstad, Karl and Olsson, Peterx and Henriksson, Gunnel},
  issn         = {2326-5205},
  language     = {eng},
  number       = {9},
  pages        = {2427--2436},
  publisher    = {Wiley-Blackwell},
  series       = {Arthritis & rheumatology (Hoboken, N.J.)},
  title        = {Autoantibody profiling can predict primary Sjögren's syndrome years before diagnosis and identify those with early onset and severe disease course.},
  url          = {http://dx.doi.org/10.1002/art.39214},
  volume       = {67},
  year         = {2015},
}