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Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin.

Ekstrand, Matias; Gustafsson Trajkovska, Maria; Perman-Sundelin, Jeanna; Fogelstrand, Per; Adiels, Martin; Johansson, Martin LU ; Mattsson-Hultén, Lillemor; Borén, Jan and Levin, Max (2015) In PLoS ONE 10(6).
Abstract
The first objective was to investigate if intracellular and extracellular levels of reactive oxygen species (ROS) within the mouse aorta increase before or after diet-induced lesion formation. The second objective was to investigate if intracellular and extracellular ROS correlates to cell composition in atherosclerotic lesions. The third objective was to investigate if intracellular and extracellular ROS levels within established atherosclerotic lesions can be reduced by lipid lowering by diet or atorvastatin.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
6
publisher
Public Library of Science
external identifiers
  • pmid:26098110
  • wos:000356835800120
  • scopus:84939200015
ISSN
1932-6203
DOI
10.1371/journal.pone.0130898
language
English
LU publication?
yes
id
6330c8b4-c7af-4eb2-908d-36b009084898 (old id 7478602)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26098110?dopt=Abstract
date added to LUP
2015-07-09 19:47:26
date last changed
2017-11-05 03:50:35
@article{6330c8b4-c7af-4eb2-908d-36b009084898,
  abstract     = {The first objective was to investigate if intracellular and extracellular levels of reactive oxygen species (ROS) within the mouse aorta increase before or after diet-induced lesion formation. The second objective was to investigate if intracellular and extracellular ROS correlates to cell composition in atherosclerotic lesions. The third objective was to investigate if intracellular and extracellular ROS levels within established atherosclerotic lesions can be reduced by lipid lowering by diet or atorvastatin.},
  articleno    = {e0130898},
  author       = {Ekstrand, Matias and Gustafsson Trajkovska, Maria and Perman-Sundelin, Jeanna and Fogelstrand, Per and Adiels, Martin and Johansson, Martin and Mattsson-Hultén, Lillemor and Borén, Jan and Levin, Max},
  issn         = {1932-6203},
  language     = {eng},
  number       = {6},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0130898},
  volume       = {10},
  year         = {2015},
}