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Physical exercise and internet-based cognitive behavioural therapy in the treatment of depression: randomised controlled trial.

Hallgren, Mats; Kraepelien, Martin; Öjehagen, Agneta LU ; Lindefors, Nils; Zeebari, Zangin; Kaldo, Viktor and Forsell, Yvonne (2015) In British Journal of Psychiatry 207(3). p.227-234
Abstract
BackgroundDepression is common and tends to be recurrent. Alternative treatments are needed that are non-stigmatising, accessible and can be prescribed by general medical practitioners.AimsTo compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive-behavioural therapy (ICBT) and treatment as usual (TAU). A secondary aim was to assess changes in self-rated work capacity.MethodA total of 946 patients diagnosed with mild to moderate depression were recruited through primary healthcare centres across Sweden and randomly assigned to one of three 12-week interventions (trail registry: KCTR study ID: KT20110063). Patients were reassessed at 3 months (response rate 78%).ResultsPatients in the... (More)
BackgroundDepression is common and tends to be recurrent. Alternative treatments are needed that are non-stigmatising, accessible and can be prescribed by general medical practitioners.AimsTo compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive-behavioural therapy (ICBT) and treatment as usual (TAU). A secondary aim was to assess changes in self-rated work capacity.MethodA total of 946 patients diagnosed with mild to moderate depression were recruited through primary healthcare centres across Sweden and randomly assigned to one of three 12-week interventions (trail registry: KCTR study ID: KT20110063). Patients were reassessed at 3 months (response rate 78%).ResultsPatients in the exercise and ICBT groups reported larger improvements in depressive symptoms compared with TAU. Work capacity improved over time in all three groups (no significant differences).ConclusionsExercise and ICBT were more effective than TAU by a general medical practitioner, and both represent promising non-stigmatising treatment alternatives for patients with mild to moderate depression. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Psychiatry
volume
207
issue
3
pages
227 - 234
publisher
Royal College of Psychiatrists
external identifiers
  • pmid:26089305
  • wos:000361080900009
  • scopus:84938957671
ISSN
0007-1250
DOI
10.1192/bjp.bp.114.160101
language
English
LU publication?
yes
id
b5da3539-f358-4ce7-9261-cfb121f7cdd3 (old id 7484712)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26089305?dopt=Abstract
date added to LUP
2015-07-08 20:39:01
date last changed
2017-10-08 03:12:20
@article{b5da3539-f358-4ce7-9261-cfb121f7cdd3,
  abstract     = {BackgroundDepression is common and tends to be recurrent. Alternative treatments are needed that are non-stigmatising, accessible and can be prescribed by general medical practitioners.AimsTo compare the effectiveness of three interventions for depression: physical exercise, internet-based cognitive-behavioural therapy (ICBT) and treatment as usual (TAU). A secondary aim was to assess changes in self-rated work capacity.MethodA total of 946 patients diagnosed with mild to moderate depression were recruited through primary healthcare centres across Sweden and randomly assigned to one of three 12-week interventions (trail registry: KCTR study ID: KT20110063). Patients were reassessed at 3 months (response rate 78%).ResultsPatients in the exercise and ICBT groups reported larger improvements in depressive symptoms compared with TAU. Work capacity improved over time in all three groups (no significant differences).ConclusionsExercise and ICBT were more effective than TAU by a general medical practitioner, and both represent promising non-stigmatising treatment alternatives for patients with mild to moderate depression.},
  author       = {Hallgren, Mats and Kraepelien, Martin and Öjehagen, Agneta and Lindefors, Nils and Zeebari, Zangin and Kaldo, Viktor and Forsell, Yvonne},
  issn         = {0007-1250},
  language     = {eng},
  number       = {3},
  pages        = {227--234},
  publisher    = {Royal College of Psychiatrists},
  series       = {British Journal of Psychiatry},
  title        = {Physical exercise and internet-based cognitive behavioural therapy in the treatment of depression: randomised controlled trial.},
  url          = {http://dx.doi.org/10.1192/bjp.bp.114.160101},
  volume       = {207},
  year         = {2015},
}