Spontaneous activity and stretch-induced contractile differentiation are reduced in vascular smooth muscle of miR-143/145 knockout mice.
(2015) In Acta Physiologica 215(3). p.133-143- Abstract
- Stretch is essential for maintaining the contractile phenotype of vascular smooth muscle cells, and small non-coding microRNAs are known to be important in this process. Using a Dicer knockout model, we have previously reported that microRNAs are essential for stretch-induced differentiation and regulation of L-type calcium channel expression. The aim of this study was to investigate the importance of the smooth muscle-enriched miR-143/145 microRNA cluster for stretch-induced differentiation of the portal vein.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7487582
- author
- Bhattachariya, Anirban LU ; Dahan, Diana LU ; Ekman, Mari LU ; Boettger, T ; Braun, T ; Swärd, Karl LU ; Hellstrand, Per LU and Albinsson, Sebastian LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Physiologica
- volume
- 215
- issue
- 3
- pages
- 133 - 143
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:26052659
- wos:000362894200006
- scopus:84943579848
- pmid:26052659
- ISSN
- 1748-1716
- DOI
- 10.1111/apha.12536
- language
- English
- LU publication?
- yes
- id
- 27a985e4-3fd7-47df-8d32-295ed9c78d1a (old id 7487582)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26052659?dopt=Abstract
- date added to LUP
- 2016-04-01 10:14:05
- date last changed
- 2022-04-27 20:00:22
@article{27a985e4-3fd7-47df-8d32-295ed9c78d1a, abstract = {{Stretch is essential for maintaining the contractile phenotype of vascular smooth muscle cells, and small non-coding microRNAs are known to be important in this process. Using a Dicer knockout model, we have previously reported that microRNAs are essential for stretch-induced differentiation and regulation of L-type calcium channel expression. The aim of this study was to investigate the importance of the smooth muscle-enriched miR-143/145 microRNA cluster for stretch-induced differentiation of the portal vein.}}, author = {{Bhattachariya, Anirban and Dahan, Diana and Ekman, Mari and Boettger, T and Braun, T and Swärd, Karl and Hellstrand, Per and Albinsson, Sebastian}}, issn = {{1748-1716}}, language = {{eng}}, number = {{3}}, pages = {{133--143}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Physiologica}}, title = {{Spontaneous activity and stretch-induced contractile differentiation are reduced in vascular smooth muscle of miR-143/145 knockout mice.}}, url = {{https://lup.lub.lu.se/search/files/1675749/7852855.pdf}}, doi = {{10.1111/apha.12536}}, volume = {{215}}, year = {{2015}}, }