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Feasibility of micro-computed tomography for evaluating anatomical landmarks in temporal bone specimens

Pellby, David LU ; Celander, My LU ; Peruzzi, Niccolo LU orcid ; Siemund, Roger LU ; Nilsson, Margareta LU ; Bech, Martin LU orcid and Aurumskjöld, Marie Louise LU (2026) In Radiation Protection Dosimetry 202(3-4). p.180-186
Abstract

Photon counting computed tomography (PCCT) provides exceptional image quality with reduced radiation dose in temporal bone imaging and is emerging as a potential new gold standard. This study aims to assess the feasibility of an in-house micro-computed tomography (micro-CT) system equipped with Photon Counting Detector (PCD) technology and to compare it with a clinical PCCT scanner for temporal bone evaluation. A fresh-frozen temporal bone specimen was scanned with both systems, focusing on four anatomical landmarks: stapes, lateral semicircular canal, tympanic segment of the facial nerve canal, and modiolus. Two radiologists assessed the landmarks, using clinical PCCT images as the reference. The in-house micro-CT achieved a high... (More)

Photon counting computed tomography (PCCT) provides exceptional image quality with reduced radiation dose in temporal bone imaging and is emerging as a potential new gold standard. This study aims to assess the feasibility of an in-house micro-computed tomography (micro-CT) system equipped with Photon Counting Detector (PCD) technology and to compare it with a clinical PCCT scanner for temporal bone evaluation. A fresh-frozen temporal bone specimen was scanned with both systems, focusing on four anatomical landmarks: stapes, lateral semicircular canal, tympanic segment of the facial nerve canal, and modiolus. Two radiologists assessed the landmarks, using clinical PCCT images as the reference. The in-house micro-CT achieved a high resolution of 32.5 μm, enabling excellent visualization of the landmarks. These results demonstrate that the PCD micro-CT system is a feasible and valuable tool, offering important insights into the complex structures of the middle and inner ear for advancing both clinical and research applications.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Radiation Protection Dosimetry
volume
202
issue
3-4
pages
7 pages
publisher
Oxford University Press
external identifiers
  • scopus:105032789304
  • pmid:41821444
ISSN
0144-8420
DOI
10.1093/rpd/ncaf146
language
English
LU publication?
yes
additional info
Publisher Copyright: © The Author(s) 2026. Published by Oxford University Press. All rights reserved.
id
750961b5-99a5-4e66-8aa3-c27c115d29a6
date added to LUP
2026-05-19 14:43:40
date last changed
2026-07-01 23:46:25
@article{750961b5-99a5-4e66-8aa3-c27c115d29a6,
  abstract     = {{<p>Photon counting computed tomography (PCCT) provides exceptional image quality with reduced radiation dose in temporal bone imaging and is emerging as a potential new gold standard. This study aims to assess the feasibility of an in-house micro-computed tomography (micro-CT) system equipped with Photon Counting Detector (PCD) technology and to compare it with a clinical PCCT scanner for temporal bone evaluation. A fresh-frozen temporal bone specimen was scanned with both systems, focusing on four anatomical landmarks: stapes, lateral semicircular canal, tympanic segment of the facial nerve canal, and modiolus. Two radiologists assessed the landmarks, using clinical PCCT images as the reference. The in-house micro-CT achieved a high resolution of 32.5 μm, enabling excellent visualization of the landmarks. These results demonstrate that the PCD micro-CT system is a feasible and valuable tool, offering important insights into the complex structures of the middle and inner ear for advancing both clinical and research applications.</p>}},
  author       = {{Pellby, David and Celander, My and Peruzzi, Niccolo and Siemund, Roger and Nilsson, Margareta and Bech, Martin and Aurumskjöld, Marie Louise}},
  issn         = {{0144-8420}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{3-4}},
  pages        = {{180--186}},
  publisher    = {{Oxford University Press}},
  series       = {{Radiation Protection Dosimetry}},
  title        = {{Feasibility of micro-computed tomography for evaluating anatomical landmarks in temporal bone specimens}},
  url          = {{http://dx.doi.org/10.1093/rpd/ncaf146}},
  doi          = {{10.1093/rpd/ncaf146}},
  volume       = {{202}},
  year         = {{2026}},
}