Incompleteness as a clinical characteristic and predictor of treatment outcome in obsessive-compulsive disorder
(2024) In Journal of Obsessive-Compulsive and Related Disorders 42.- Abstract
Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p < 0.001), psychiatric comorbidity (β = 0.23, [95%... (More)
Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p < 0.001), psychiatric comorbidity (β = 0.23, [95% CI 0.21 to 0.25], p < 0.05) and self-reported symptom severity (Y-BOCS-SR β = 0.35, [95% CI 0.27 to 0.43], p < 0.001; OCI-R β = 0.46, [95% CI 0.34 to 0.59], p < 0.001). Results showed that higher degree of incompleteness predicted a worse treatment outcome on clinician-rated, but not self-rated, measures of symptom severity. Participants with a high (vs. low) degree of incompleteness were less likely to be classified as responders (39% vs. 52%) and remitters (10% vs. 34%) at post-treatment. The results suggest that incompleteness is a clinically relevant feature of OCD, which may require treatment adaptations for some patients but more research is needed to confirm that the findings are not entirely due to measurement error.
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- author
- Lundström, Lina ; Ivanova, Ekaterina ; Mataix-Cols, David LU ; Flygare, Oskar ; Cervin, Matti LU ; Rück, Christian and Andersson, Erik
- organization
- publishing date
- 2024-07
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- incompleteness, Internet-delivered CBT, OCD, Treatment
- in
- Journal of Obsessive-Compulsive and Related Disorders
- volume
- 42
- article number
- 100880
- publisher
- Elsevier
- external identifiers
-
- scopus:85194479681
- ISSN
- 2211-3649
- DOI
- 10.1016/j.jocrd.2024.100880
- language
- English
- LU publication?
- yes
- id
- 757da262-b116-4255-b483-19e0efcbb39b
- date added to LUP
- 2024-08-12 14:58:43
- date last changed
- 2024-08-12 14:58:43
@article{757da262-b116-4255-b483-19e0efcbb39b, abstract = {{<p>Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p < 0.001), psychiatric comorbidity (β = 0.23, [95% CI 0.21 to 0.25], p < 0.05) and self-reported symptom severity (Y-BOCS-SR β = 0.35, [95% CI 0.27 to 0.43], p < 0.001; OCI-R β = 0.46, [95% CI 0.34 to 0.59], p < 0.001). Results showed that higher degree of incompleteness predicted a worse treatment outcome on clinician-rated, but not self-rated, measures of symptom severity. Participants with a high (vs. low) degree of incompleteness were less likely to be classified as responders (39% vs. 52%) and remitters (10% vs. 34%) at post-treatment. The results suggest that incompleteness is a clinically relevant feature of OCD, which may require treatment adaptations for some patients but more research is needed to confirm that the findings are not entirely due to measurement error.</p>}}, author = {{Lundström, Lina and Ivanova, Ekaterina and Mataix-Cols, David and Flygare, Oskar and Cervin, Matti and Rück, Christian and Andersson, Erik}}, issn = {{2211-3649}}, keywords = {{incompleteness; Internet-delivered CBT; OCD; Treatment}}, language = {{eng}}, publisher = {{Elsevier}}, series = {{Journal of Obsessive-Compulsive and Related Disorders}}, title = {{Incompleteness as a clinical characteristic and predictor of treatment outcome in obsessive-compulsive disorder}}, url = {{http://dx.doi.org/10.1016/j.jocrd.2024.100880}}, doi = {{10.1016/j.jocrd.2024.100880}}, volume = {{42}}, year = {{2024}}, }