Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Incompleteness as a clinical characteristic and predictor of treatment outcome in obsessive-compulsive disorder

Lundström, Lina ; Ivanova, Ekaterina ; Mataix-Cols, David LU ; Flygare, Oskar ; Cervin, Matti LU ; Rück, Christian and Andersson, Erik (2024) In Journal of Obsessive-Compulsive and Related Disorders 42.
Abstract

Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p < 0.001), psychiatric comorbidity (β = 0.23, [95%... (More)

Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p < 0.001), psychiatric comorbidity (β = 0.23, [95% CI 0.21 to 0.25], p < 0.05) and self-reported symptom severity (Y-BOCS-SR β = 0.35, [95% CI 0.27 to 0.43], p < 0.001; OCI-R β = 0.46, [95% CI 0.34 to 0.59], p < 0.001). Results showed that higher degree of incompleteness predicted a worse treatment outcome on clinician-rated, but not self-rated, measures of symptom severity. Participants with a high (vs. low) degree of incompleteness were less likely to be classified as responders (39% vs. 52%) and remitters (10% vs. 34%) at post-treatment. The results suggest that incompleteness is a clinically relevant feature of OCD, which may require treatment adaptations for some patients but more research is needed to confirm that the findings are not entirely due to measurement error.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
incompleteness, Internet-delivered CBT, OCD, Treatment
in
Journal of Obsessive-Compulsive and Related Disorders
volume
42
article number
100880
publisher
Elsevier
external identifiers
  • scopus:85194479681
ISSN
2211-3649
DOI
10.1016/j.jocrd.2024.100880
language
English
LU publication?
yes
id
757da262-b116-4255-b483-19e0efcbb39b
date added to LUP
2024-08-12 14:58:43
date last changed
2024-08-12 14:58:43
@article{757da262-b116-4255-b483-19e0efcbb39b,
  abstract     = {{<p>Incompleteness, that is, a feeling that things are “not just right”, is an understudied symptom of obsessive-compulsive disorder (OCD). We used data from 167 adult individuals with OCD who received internet-delivered cognitive behaviour therapy (ICBT) to examine how incompleteness was associated with clinical characteristics and treatment outcomes. Incompleteness was assessed using the Obsessive-Compulsive Trait Core Dimensions Questionnaire (OCTCDQ). Results showed that the proposed two-factor structure of the OCTCDQ had adequate model/data fit in the present sample. Incompleteness was positively associated with baseline symmetry/ordering symptoms (β = 0.52, [95% CI 0.48 to 0.56], p &lt; 0.001), psychiatric comorbidity (β = 0.23, [95% CI 0.21 to 0.25], p &lt; 0.05) and self-reported symptom severity (Y-BOCS-SR β = 0.35, [95% CI 0.27 to 0.43], p &lt; 0.001; OCI-R β = 0.46, [95% CI 0.34 to 0.59], p &lt; 0.001). Results showed that higher degree of incompleteness predicted a worse treatment outcome on clinician-rated, but not self-rated, measures of symptom severity. Participants with a high (vs. low) degree of incompleteness were less likely to be classified as responders (39% vs. 52%) and remitters (10% vs. 34%) at post-treatment. The results suggest that incompleteness is a clinically relevant feature of OCD, which may require treatment adaptations for some patients but more research is needed to confirm that the findings are not entirely due to measurement error.</p>}},
  author       = {{Lundström, Lina and Ivanova, Ekaterina and Mataix-Cols, David and Flygare, Oskar and Cervin, Matti and Rück, Christian and Andersson, Erik}},
  issn         = {{2211-3649}},
  keywords     = {{incompleteness; Internet-delivered CBT; OCD; Treatment}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Obsessive-Compulsive and Related Disorders}},
  title        = {{Incompleteness as a clinical characteristic and predictor of treatment outcome in obsessive-compulsive disorder}},
  url          = {{http://dx.doi.org/10.1016/j.jocrd.2024.100880}},
  doi          = {{10.1016/j.jocrd.2024.100880}},
  volume       = {{42}},
  year         = {{2024}},
}