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Kick-starting the cancer-immunity cycle by targeting CD40

Ellmark, Peter LU ; Mangsbo, S. M.; Furebring, C.; Totterman, T. H. and Norlen, P. (2015) In OncoImmunology 4(7). p.1011484-1011484
Abstract
Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for combination regimens.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
CD40, PD-1, agonistic antibody, immunooncology
in
OncoImmunology
volume
4
issue
7
pages
1011484 - 1011484
publisher
Landes Bioscience
external identifiers
  • wos:000356964800002
  • pmid:26140231
  • scopus:84944453397
ISSN
2162-4011
DOI
10.1080/2162402X.2015.1011484
language
English
LU publication?
yes
id
d878c92b-517a-44d0-9220-7543c0873d02 (old id 7596483)
date added to LUP
2015-07-21 10:02:55
date last changed
2017-01-22 03:08:31
@misc{d878c92b-517a-44d0-9220-7543c0873d02,
  abstract     = {Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for combination regimens.},
  author       = {Ellmark, Peter and Mangsbo, S. M. and Furebring, C. and Totterman, T. H. and Norlen, P.},
  issn         = {2162-4011},
  keyword      = {CD40,PD-1,agonistic antibody,immunooncology},
  language     = {eng},
  number       = {7},
  pages        = {1011484--1011484},
  publisher    = {Landes Bioscience},
  series       = {OncoImmunology},
  title        = {Kick-starting the cancer-immunity cycle by targeting CD40},
  url          = {http://dx.doi.org/10.1080/2162402X.2015.1011484},
  volume       = {4},
  year         = {2015},
}