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Risk and risk estimation of placental abruption.

Lindqvist, Pelle LU and Happach, Catharina (2006) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 126(Sep 29). p.160-164
Abstract
Objective: Several variables related to increased risk of placental abruption are also risk factors for venous thromboembolism. Prior second trimester-, third trimester, and repeated fetal loss are reported to be associated to thrombophilias. However, it is yet not known if they are also related to placental abruption. Study design: A retrospective case-control study of 161 women with placental abruption and 2371 unselected gravidae without placental abruption. The medical files were scrutinized and the selected variables were investigated in relation to the development of placental abruption. Results: As compared to controls, previous second trimester-, third trimester-, repeated fetal loss, and prior placental abruption were related to a... (More)
Objective: Several variables related to increased risk of placental abruption are also risk factors for venous thromboembolism. Prior second trimester-, third trimester, and repeated fetal loss are reported to be associated to thrombophilias. However, it is yet not known if they are also related to placental abruption. Study design: A retrospective case-control study of 161 women with placental abruption and 2371 unselected gravidae without placental abruption. The medical files were scrutinized and the selected variables were investigated in relation to the development of placental abruption. Results: As compared to controls, previous second trimester-, third trimester-, repeated fetal loss, and prior placental abruption were related to a 3-, 13-, 3-, and a 25-fold increased risk of placental abruption, respectively. Several other factors were associated with a roughly three-fold increased risk such as: preeclampsia, IUGR, high maternal age (>35), family history of venous thromboembolism, smoking, and multiple birth. A risk score was created and as compared with those with no risk factors present, the risk of placental abruption was increasing from 2.5-fold for those with risk score = 1, to almost 100-fold for risk score 4 or above. Conclusion: Easily obtainable information might be used to classify the risk of placental abruption. (C) 2005 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
placental abruption, risk score, fetal loss, prediction
in
European Journal of Obstetrics, Gynecology, and Reproductive Biology
volume
126
issue
Sep 29
pages
160 - 164
publisher
Elsevier
external identifiers
  • pmid:16202500
  • wos:000238461300004
  • scopus:33746828281
ISSN
0301-2115
DOI
10.1016/j.ejogrb.2005.08.003
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Obstetrics and Gynaecology (013242700), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
id
75998146-fcf8-4596-8636-19d208668089 (old id 144882)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16202500&dopt=Abstract
date added to LUP
2016-04-01 11:47:56
date last changed
2019-11-20 01:53:02
@article{75998146-fcf8-4596-8636-19d208668089,
  abstract     = {Objective: Several variables related to increased risk of placental abruption are also risk factors for venous thromboembolism. Prior second trimester-, third trimester, and repeated fetal loss are reported to be associated to thrombophilias. However, it is yet not known if they are also related to placental abruption. Study design: A retrospective case-control study of 161 women with placental abruption and 2371 unselected gravidae without placental abruption. The medical files were scrutinized and the selected variables were investigated in relation to the development of placental abruption. Results: As compared to controls, previous second trimester-, third trimester-, repeated fetal loss, and prior placental abruption were related to a 3-, 13-, 3-, and a 25-fold increased risk of placental abruption, respectively. Several other factors were associated with a roughly three-fold increased risk such as: preeclampsia, IUGR, high maternal age (>35), family history of venous thromboembolism, smoking, and multiple birth. A risk score was created and as compared with those with no risk factors present, the risk of placental abruption was increasing from 2.5-fold for those with risk score = 1, to almost 100-fold for risk score 4 or above. Conclusion: Easily obtainable information might be used to classify the risk of placental abruption. (C) 2005 Elsevier Ireland Ltd. All rights reserved.},
  author       = {Lindqvist, Pelle and Happach, Catharina},
  issn         = {0301-2115},
  language     = {eng},
  number       = {Sep 29},
  pages        = {160--164},
  publisher    = {Elsevier},
  series       = {European Journal of Obstetrics, Gynecology, and Reproductive Biology},
  title        = {Risk and risk estimation of placental abruption.},
  url          = {https://lup.lub.lu.se/search/ws/files/2646657/1059998.pdf},
  doi          = {10.1016/j.ejogrb.2005.08.003},
  volume       = {126},
  year         = {2006},
}