The Swedish National Pediatric Cataract Register (PECARE) : incidence and onset of postoperative glaucoma
(2020) In Acta Ophthalmologica 98(7). p.654-661- Abstract
Purpose: The aim was to report cumulative incidence and time of onset of postoperative glaucoma in a paediatric early cataract surgery cohort. Methods: Data were retrieved from the Pediatric Cataract Register (PECARE), a prospective register of Swedish cataract operations before 8 years of age. All eyes with surgery between January 2007 and December 2014 and a registered follow-up were included. Cataracts caused by uveitis, trauma or coexisting congenital glaucoma were excluded. Glaucoma was defined as early onset if diagnosed within a year after surgery and late onset if diagnosed later. Results: The study included 288 eyes in 207 children (106 girls), 81 with bilateral and 126 with unilateral cataracts, with a mean follow-up of 3.31 ±... (More)
Purpose: The aim was to report cumulative incidence and time of onset of postoperative glaucoma in a paediatric early cataract surgery cohort. Methods: Data were retrieved from the Pediatric Cataract Register (PECARE), a prospective register of Swedish cataract operations before 8 years of age. All eyes with surgery between January 2007 and December 2014 and a registered follow-up were included. Cataracts caused by uveitis, trauma or coexisting congenital glaucoma were excluded. Glaucoma was defined as early onset if diagnosed within a year after surgery and late onset if diagnosed later. Results: The study included 288 eyes in 207 children (106 girls), 81 with bilateral and 126 with unilateral cataracts, with a mean follow-up of 3.31 ± 1.77 years. Of the 288, 168 (58.3%) had surgery before 3 months of age; most of these 92.3% (155/168) were defined as dense, 208 (72.2%) were below 1 year of age. Cumulative incidence of surgically treated glaucoma among individuals was 23.7% (49/207). Median time to glaucoma onset was 0.91 years (range: 0.05–4.97 years) for eyes. Early-onset glaucoma was found in 98 % (63/64), and late onset in 2% (1/64). Conclusion: In this paediatric cataract cohort, a majority of eyes had surgery before 3 months of age (58.3%). Secondary glaucoma-onset peaked within the first postoperative year, with a cumulative incidence of 23.7%. Surgery performed after the first month of life, resulted in a lower glaucoma rate. Long-term follow-up will reveal whether the low rate of late-onset glaucoma with early surgery will last, and if so, the consequences.
(Less)
- author
- Nyström, Alf LU ; Haargaard, Birgitte ; Rosensvärd, Annika ; Tornqvist, Kristina LU and Magnusson, Gunilla
- organization
- publishing date
- 2020-11
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- glaucoma incidence, glaucoma onset, paediatric cataract surgery, postoperative glaucoma, registry data
- in
- Acta Ophthalmologica
- volume
- 98
- issue
- 7
- pages
- 8 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85083056881
- pmid:32274899
- ISSN
- 1755-375X
- DOI
- 10.1111/aos.14414
- language
- English
- LU publication?
- yes
- id
- 75cb8125-6921-4350-81b4-322a2cd93553
- date added to LUP
- 2020-05-08 15:58:23
- date last changed
- 2024-06-12 13:29:55
@article{75cb8125-6921-4350-81b4-322a2cd93553,
abstract = {{<p>Purpose: The aim was to report cumulative incidence and time of onset of postoperative glaucoma in a paediatric early cataract surgery cohort. Methods: Data were retrieved from the Pediatric Cataract Register (PECARE), a prospective register of Swedish cataract operations before 8 years of age. All eyes with surgery between January 2007 and December 2014 and a registered follow-up were included. Cataracts caused by uveitis, trauma or coexisting congenital glaucoma were excluded. Glaucoma was defined as early onset if diagnosed within a year after surgery and late onset if diagnosed later. Results: The study included 288 eyes in 207 children (106 girls), 81 with bilateral and 126 with unilateral cataracts, with a mean follow-up of 3.31 ± 1.77 years. Of the 288, 168 (58.3%) had surgery before 3 months of age; most of these 92.3% (155/168) were defined as dense, 208 (72.2%) were below 1 year of age. Cumulative incidence of surgically treated glaucoma among individuals was 23.7% (49/207). Median time to glaucoma onset was 0.91 years (range: 0.05–4.97 years) for eyes. Early-onset glaucoma was found in 98 % (63/64), and late onset in 2% (1/64). Conclusion: In this paediatric cataract cohort, a majority of eyes had surgery before 3 months of age (58.3%). Secondary glaucoma-onset peaked within the first postoperative year, with a cumulative incidence of 23.7%. Surgery performed after the first month of life, resulted in a lower glaucoma rate. Long-term follow-up will reveal whether the low rate of late-onset glaucoma with early surgery will last, and if so, the consequences.</p>}},
author = {{Nyström, Alf and Haargaard, Birgitte and Rosensvärd, Annika and Tornqvist, Kristina and Magnusson, Gunilla}},
issn = {{1755-375X}},
keywords = {{glaucoma incidence; glaucoma onset; paediatric cataract surgery; postoperative glaucoma; registry data}},
language = {{eng}},
number = {{7}},
pages = {{654--661}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Ophthalmologica}},
title = {{The Swedish National Pediatric Cataract Register (PECARE) : incidence and onset of postoperative glaucoma}},
url = {{http://dx.doi.org/10.1111/aos.14414}},
doi = {{10.1111/aos.14414}},
volume = {{98}},
year = {{2020}},
}