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Longitudinal movements and resulting shear strain of the arterial wall

Cinthio, Magnus LU ; Rydén Ahlgren, Åsa LU ; Bergkvist, Jonas LU ; Jansson, Tomas LU ; Persson, Hans W LU and Lindström, Kjell LU (2006) In American Journal of Physiology: Heart and Circulatory Physiology 291(1). p.394-402
Abstract
There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal movement of the intima-media complex could be observed in all the subjects. An antegrade longitudinal movement, i.e., in the direction of blood flow, in early systole [ 0.39 mm ( SD 0.26)] was followed by a retrograde longitudinal movement, i.e., in the direction opposite blood flow [ -0.52 mm ( SD 0.27)], later in systole and a second antegrade... (More)
There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal movement of the intima-media complex could be observed in all the subjects. An antegrade longitudinal movement, i.e., in the direction of blood flow, in early systole [ 0.39 mm ( SD 0.26)] was followed by a retrograde longitudinal movement, i.e., in the direction opposite blood flow [ -0.52 mm ( SD 0.27)], later in systole and a second antegrade longitudinal movement [ 0.41 mm ( SD 0.33)] in diastole. The corresponding diameter change was 0.65 mm ( SD 0.19). The adventitial region showed the same basic pattern of longitudinal movement; however, the magnitude of the movements was smaller than that of the intimamedia complex, thereby introducing shear strain and, thus, shear stress within the wall [ maximum shear strain between the intima-media complex and the adventitial region was 0.36 rad ( SD 0.26). These phenomena have not previously been described. Measurements were also performed on the abdominal aorta ( n = 3) and brachial ( n = 3) and popliteal ( n = 3) arteries. Our new information seems to be of fundamental importance for further study and evaluation of vascular biology and hemodynamics and, thus, for study of atherosclerosis and vascular diseases. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
arterial wall movements, shearing, vascular ultrasound, strain in arteries, carotid artery, vascular mechanics
in
American Journal of Physiology: Heart and Circulatory Physiology
volume
291
issue
1
pages
394 - 402
publisher
American Physiological Society
external identifiers
  • pmid:16473960
  • wos:000238262500049
  • scopus:33745726606
ISSN
1522-1539
DOI
10.1152/ajpheart.00988.2005
language
English
LU publication?
yes
id
7641f1ec-ab96-4256-a9bb-cf878ed7619a (old id 406342)
date added to LUP
2007-10-01 19:00:01
date last changed
2018-10-07 03:39:42
@article{7641f1ec-ab96-4256-a9bb-cf878ed7619a,
  abstract     = {There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal movement of the intima-media complex could be observed in all the subjects. An antegrade longitudinal movement, i.e., in the direction of blood flow, in early systole [ 0.39 mm ( SD 0.26)] was followed by a retrograde longitudinal movement, i.e., in the direction opposite blood flow [ -0.52 mm ( SD 0.27)], later in systole and a second antegrade longitudinal movement [ 0.41 mm ( SD 0.33)] in diastole. The corresponding diameter change was 0.65 mm ( SD 0.19). The adventitial region showed the same basic pattern of longitudinal movement; however, the magnitude of the movements was smaller than that of the intimamedia complex, thereby introducing shear strain and, thus, shear stress within the wall [ maximum shear strain between the intima-media complex and the adventitial region was 0.36 rad ( SD 0.26). These phenomena have not previously been described. Measurements were also performed on the abdominal aorta ( n = 3) and brachial ( n = 3) and popliteal ( n = 3) arteries. Our new information seems to be of fundamental importance for further study and evaluation of vascular biology and hemodynamics and, thus, for study of atherosclerosis and vascular diseases.},
  author       = {Cinthio, Magnus and Rydén Ahlgren, Åsa and Bergkvist, Jonas and Jansson, Tomas and Persson, Hans W and Lindström, Kjell},
  issn         = {1522-1539},
  keyword      = {arterial wall movements,shearing,vascular ultrasound,strain in arteries,carotid artery,vascular mechanics},
  language     = {eng},
  number       = {1},
  pages        = {394--402},
  publisher    = {American Physiological Society},
  series       = {American Journal of Physiology: Heart and Circulatory Physiology},
  title        = {Longitudinal movements and resulting shear strain of the arterial wall},
  url          = {http://dx.doi.org/10.1152/ajpheart.00988.2005},
  volume       = {291},
  year         = {2006},
}