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Pervasive Refusal Syndrome : Three Case Reports - Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?

Jarbin, Håkan LU ; Saldeen, Ann Sofie and Forslund, Carl Magnus LU (2022) In Case Reports in Psychiatry 2022.
Abstract

Background. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been suggested as a predisposing factor but largely lacks support for typical cases of PRS. Treatment is not evidence-based and described as requiring a lengthy inpatient stay with a very gradual and sensitive rehabilitation program. Case Presentations. Three cases of pervasive refusal syndrome (PRS) in girls aged 9-16 years are presented to report autism as a predisposing factor and to discuss gentle coercion as part of the management strategy to... (More)

Background. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been suggested as a predisposing factor but largely lacks support for typical cases of PRS. Treatment is not evidence-based and described as requiring a lengthy inpatient stay with a very gradual and sensitive rehabilitation program. Case Presentations. Three cases of pervasive refusal syndrome (PRS) in girls aged 9-16 years are presented to report autism as a predisposing factor and to discuss gentle coercion as part of the management strategy to speed up the lengthy recovery. The cases, which met the proposed criteria and typical background characteristics, were noted with the addition of undiagnosed autism in two cases. The duration of inpatient admission was 8-14 months. Disease duration was 15-36 months. An adequate but negative lorazepam trial to rule out catatonia was carried out. Treatment was in one case successfully expedited with gentle coercion within a transparent management plan. Rehabilitation was slower in PRS with comorbid autism; additionally, accommodations to school and living support needed to be put in place. Conclusions. PRS is a useful clinical entity and best perceived as a primitive reaction to overwhelming stress rather than as catatonia. Autism might be another predisposing factor and needs to be assessed. A psychoeducational approach and a clear management plan support rehabilitation. A gentle coercion might hasten recovery.

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type
Contribution to journal
publication status
published
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in
Case Reports in Psychiatry
volume
2022
article number
2258180
publisher
Hindawi Limited
external identifiers
  • scopus:85127987565
  • pmid:35371579
ISSN
2090-682X
DOI
10.1155/2022/2258180
language
English
LU publication?
yes
id
771795f2-3077-4dda-b88e-3c088c6a1780
date added to LUP
2022-06-10 10:48:54
date last changed
2024-05-30 16:29:41
@article{771795f2-3077-4dda-b88e-3c088c6a1780,
  abstract     = {{<p>Background. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been suggested as a predisposing factor but largely lacks support for typical cases of PRS. Treatment is not evidence-based and described as requiring a lengthy inpatient stay with a very gradual and sensitive rehabilitation program. Case Presentations. Three cases of pervasive refusal syndrome (PRS) in girls aged 9-16 years are presented to report autism as a predisposing factor and to discuss gentle coercion as part of the management strategy to speed up the lengthy recovery. The cases, which met the proposed criteria and typical background characteristics, were noted with the addition of undiagnosed autism in two cases. The duration of inpatient admission was 8-14 months. Disease duration was 15-36 months. An adequate but negative lorazepam trial to rule out catatonia was carried out. Treatment was in one case successfully expedited with gentle coercion within a transparent management plan. Rehabilitation was slower in PRS with comorbid autism; additionally, accommodations to school and living support needed to be put in place. Conclusions. PRS is a useful clinical entity and best perceived as a primitive reaction to overwhelming stress rather than as catatonia. Autism might be another predisposing factor and needs to be assessed. A psychoeducational approach and a clear management plan support rehabilitation. A gentle coercion might hasten recovery. </p>}},
  author       = {{Jarbin, Håkan and Saldeen, Ann Sofie and Forslund, Carl Magnus}},
  issn         = {{2090-682X}},
  language     = {{eng}},
  publisher    = {{Hindawi Limited}},
  series       = {{Case Reports in Psychiatry}},
  title        = {{Pervasive Refusal Syndrome : Three Case Reports - Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?}},
  url          = {{http://dx.doi.org/10.1155/2022/2258180}},
  doi          = {{10.1155/2022/2258180}},
  volume       = {{2022}},
  year         = {{2022}},
}