Which breathlessness dimensions associate most strongly with fatigue?-The populationbased VASCOL study of elderly men
(2023) In PLoS ONE 18(12 December).- Abstract
Background Breathlessness and fatigue are common symptoms in older people. We aimed to evaluate how different breathlessness dimensions (overall intensity, unpleasantness, sensory descriptors, emotional responses) were associated with fatigue in elderly men. Methods This was a cross-sectional analysis of the population-based VAScular disease and Chronic Obstructive Lung Disease (VASCOL) study of 73-year old men. Breathlessness dimensions were assessed using the Dyspnoea-12 (D-12), Multidimensional Dyspnoea Profile (MDP), and the modified Medical Research Council (mMRC) scale. Fatigue was assessed using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) questionnaire. Clinically relevant fatigue was defined as... (More)
Background Breathlessness and fatigue are common symptoms in older people. We aimed to evaluate how different breathlessness dimensions (overall intensity, unpleasantness, sensory descriptors, emotional responses) were associated with fatigue in elderly men. Methods This was a cross-sectional analysis of the population-based VAScular disease and Chronic Obstructive Lung Disease (VASCOL) study of 73-year old men. Breathlessness dimensions were assessed using the Dyspnoea-12 (D-12), Multidimensional Dyspnoea Profile (MDP), and the modified Medical Research Council (mMRC) scale. Fatigue was assessed using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) questionnaire. Clinically relevant fatigue was defined as FACIT-F≤ 30 units. Scores were compared standardized as z-scores and analysed using linear regression, adjusted for body mass index, smoking, depression, cancer, sleep apnoea, prior cardiac surgery, respiratory and cardiovascular disease. Results Of 677 participants, 11.7% had clinically relevant fatigue. Higher breathlessness scores were associated with having worse fatigue; for D-12 total, -0.35 ([95% CI] -0.41 to -0.30) and for MDP A1, -0.24 (-0.30 to -0.18). Associations were similar across all the evaluated breathlessness dimensions even when adjusting for the potential confounders. Conclusion Breathlessness assessed using D-12 and MDP was associated with worse fatigue in elderly men, similarly across different breathlessness dimensions.
(Less)
- author
- Lucas, Cristea LU ; Max, Olsson LU ; Sandberg, Jacob LU ; Kochovska, Slavica ; Currow, David and Ekström, Magnus LU
- organization
- publishing date
- 2023-12
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 18
- issue
- 12 December
- article number
- e0296016
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- pmid:38117831
- scopus:85180295013
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0296016
- language
- English
- LU publication?
- yes
- id
- 772ef248-833a-4cec-971c-1005bd25c190
- date added to LUP
- 2024-01-08 15:27:11
- date last changed
- 2024-04-23 11:03:43
@article{772ef248-833a-4cec-971c-1005bd25c190, abstract = {{<p>Background Breathlessness and fatigue are common symptoms in older people. We aimed to evaluate how different breathlessness dimensions (overall intensity, unpleasantness, sensory descriptors, emotional responses) were associated with fatigue in elderly men. Methods This was a cross-sectional analysis of the population-based VAScular disease and Chronic Obstructive Lung Disease (VASCOL) study of 73-year old men. Breathlessness dimensions were assessed using the Dyspnoea-12 (D-12), Multidimensional Dyspnoea Profile (MDP), and the modified Medical Research Council (mMRC) scale. Fatigue was assessed using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) questionnaire. Clinically relevant fatigue was defined as FACIT-F≤ 30 units. Scores were compared standardized as z-scores and analysed using linear regression, adjusted for body mass index, smoking, depression, cancer, sleep apnoea, prior cardiac surgery, respiratory and cardiovascular disease. Results Of 677 participants, 11.7% had clinically relevant fatigue. Higher breathlessness scores were associated with having worse fatigue; for D-12 total, -0.35 ([95% CI] -0.41 to -0.30) and for MDP A1, -0.24 (-0.30 to -0.18). Associations were similar across all the evaluated breathlessness dimensions even when adjusting for the potential confounders. Conclusion Breathlessness assessed using D-12 and MDP was associated with worse fatigue in elderly men, similarly across different breathlessness dimensions.</p>}}, author = {{Lucas, Cristea and Max, Olsson and Sandberg, Jacob and Kochovska, Slavica and Currow, David and Ekström, Magnus}}, issn = {{1932-6203}}, language = {{eng}}, number = {{12 December}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Which breathlessness dimensions associate most strongly with fatigue?-The populationbased VASCOL study of elderly men}}, url = {{http://dx.doi.org/10.1371/journal.pone.0296016}}, doi = {{10.1371/journal.pone.0296016}}, volume = {{18}}, year = {{2023}}, }