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Exposure- response for biomarkers of anticoagulant effects by the oral direct thrombin inhibitor AZD0837 in patients with atrial fibrillation.

Lip, Gregory Y H ; Rasmussen, Lars H ; Olsson, Bertil LU ; Jensen, Eva ; Hamrén, Bengt ; Eriksson, Ulf and Wåhlander, Karin (2015) In British Journal of Clinical Pharmacology 80(6). p.1362-1373
Abstract
AZD0837 is a novel oral anticoagulant investigated in clinical studies for stroke prevention in patients with atrial fibrillation (AF). It is bioconverted to its active form, AR-H067637, a potent, specific and reversible thrombin inhibitor.
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Clinical Pharmacology
volume
80
issue
6
pages
1362 - 1373
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:26174611
  • wos:000367470200012
  • scopus:84957546562
  • pmid:26174611
ISSN
1365-2125
DOI
10.1111/bcp.12719
language
English
LU publication?
yes
id
988d0c32-9c6a-4a5d-b236-ddf693b03a3e (old id 7749590)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26174611?dopt=Abstract
date added to LUP
2016-04-01 09:54:50
date last changed
2022-04-12 00:07:28
@article{988d0c32-9c6a-4a5d-b236-ddf693b03a3e,
  abstract     = {{AZD0837 is a novel oral anticoagulant investigated in clinical studies for stroke prevention in patients with atrial fibrillation (AF). It is bioconverted to its active form, AR-H067637, a potent, specific and reversible thrombin inhibitor.}},
  author       = {{Lip, Gregory Y H and Rasmussen, Lars H and Olsson, Bertil and Jensen, Eva and Hamrén, Bengt and Eriksson, Ulf and Wåhlander, Karin}},
  issn         = {{1365-2125}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1362--1373}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{British Journal of Clinical Pharmacology}},
  title        = {{Exposure- response for biomarkers of anticoagulant effects by the oral direct thrombin inhibitor AZD0837 in patients with atrial fibrillation.}},
  url          = {{http://dx.doi.org/10.1111/bcp.12719}},
  doi          = {{10.1111/bcp.12719}},
  volume       = {{80}},
  year         = {{2015}},
}