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Exposure- response for biomarkers of anticoagulant effects by the oral direct thrombin inhibitor AZD0837 in patients with atrial fibrillation.

Lip, Gregory Y H; Rasmussen, Lars H; Olsson, Bertil LU ; Jensen, Eva; Hamrén, Bengt; Eriksson, Ulf and Wåhlander, Karin (2015) In British Journal of Clinical Pharmacology 80(6). p.1362-1373
Abstract
AZD0837 is a novel oral anticoagulant investigated in clinical studies for stroke prevention in patients with atrial fibrillation (AF). It is bioconverted to its active form, AR-H067637, a potent, specific and reversible thrombin inhibitor.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Clinical Pharmacology
volume
80
issue
6
pages
1362 - 1373
publisher
John Wiley & Sons
external identifiers
  • pmid:26174611
  • wos:000367470200012
  • scopus:84957546562
ISSN
1365-2125
DOI
10.1111/bcp.12719
language
English
LU publication?
yes
id
988d0c32-9c6a-4a5d-b236-ddf693b03a3e (old id 7749590)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26174611?dopt=Abstract
date added to LUP
2015-08-08 19:53:39
date last changed
2017-01-01 03:06:27
@article{988d0c32-9c6a-4a5d-b236-ddf693b03a3e,
  abstract     = {AZD0837 is a novel oral anticoagulant investigated in clinical studies for stroke prevention in patients with atrial fibrillation (AF). It is bioconverted to its active form, AR-H067637, a potent, specific and reversible thrombin inhibitor.},
  author       = {Lip, Gregory Y H and Rasmussen, Lars H and Olsson, Bertil and Jensen, Eva and Hamrén, Bengt and Eriksson, Ulf and Wåhlander, Karin},
  issn         = {1365-2125},
  language     = {eng},
  number       = {6},
  pages        = {1362--1373},
  publisher    = {John Wiley & Sons},
  series       = {British Journal of Clinical Pharmacology},
  title        = {Exposure- response for biomarkers of anticoagulant effects by the oral direct thrombin inhibitor AZD0837 in patients with atrial fibrillation.},
  url          = {http://dx.doi.org/10.1111/bcp.12719},
  volume       = {80},
  year         = {2015},
}