Real-time genomics for One Health
(2023) In Molecular Systems Biology 19(8).- Abstract
The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase... (More)
The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.
(Less)
- author
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- global health, nanopore sequencing, nature conservation, One Health, real-time genomics
- in
- Molecular Systems Biology
- volume
- 19
- issue
- 8
- article number
- e11686
- publisher
- EMBO Press
- external identifiers
-
- pmid:37325891
- scopus:85161992859
- ISSN
- 1744-4292
- DOI
- 10.15252/msb.202311686
- language
- English
- LU publication?
- yes
- id
- 776978fe-0987-4141-bfbb-cd3f1cbccff2
- date added to LUP
- 2023-10-23 13:23:04
- date last changed
- 2024-04-19 03:45:37
@article{776978fe-0987-4141-bfbb-cd3f1cbccff2,
abstract = {{<p>The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.</p>}},
author = {{Urban, Lara and Perlas, Albert and Francino, Olga and Martí-Carreras, Joan and Muga, Brenda A. and Mwangi, Jenniffer W. and Boykin Okalebo, Laura and Stanton, Jo Ann L. and Black, Amanda and Waipara, Nick and Fontsere, Claudia and Eccles, David and Urel, Harika and Reska, Tim and Morales, Hernán E. and Palmada-Flores, Marc and Marques-Bonet, Tomas and Watsa, Mrinalini and Libke, Zane and Erkenswick, Gideon and van Oosterhout, Cock}},
issn = {{1744-4292}},
keywords = {{global health; nanopore sequencing; nature conservation; One Health; real-time genomics}},
language = {{eng}},
number = {{8}},
publisher = {{EMBO Press}},
series = {{Molecular Systems Biology}},
title = {{Real-time genomics for One Health}},
url = {{http://dx.doi.org/10.15252/msb.202311686}},
doi = {{10.15252/msb.202311686}},
volume = {{19}},
year = {{2023}},
}