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Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"

Hao, Xiuli; Luethje, Freja L.; Qin, Yanan; McDevitt, Sylvia Franke; Lutay, Nataliya LU ; Hobman, Jon L.; Asiani, Karishma; Soncini, Fernando C.; German, Nadezhda and Zhang, Siyu, et al. (2015) In Applied Microbiology and Biotechnology 99(14). p.5817-5824
Abstract
The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish... (More)
The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Copper, Pathogenicity, Amoeba, Grazing resistance
in
Applied Microbiology and Biotechnology
volume
99
issue
14
pages
5817 - 5824
publisher
Springer
external identifiers
  • wos:000356806300005
  • scopus:84932196151
ISSN
1432-0614
DOI
10.1007/s00253-015-6749-0
language
English
LU publication?
yes
id
6e92ebbd-7032-4a99-a019-34d485199096 (old id 7791035)
date added to LUP
2015-09-21 08:53:36
date last changed
2017-06-11 04:18:19
@article{6e92ebbd-7032-4a99-a019-34d485199096,
  abstract     = {The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs.},
  author       = {Hao, Xiuli and Luethje, Freja L. and Qin, Yanan and McDevitt, Sylvia Franke and Lutay, Nataliya and Hobman, Jon L. and Asiani, Karishma and Soncini, Fernando C. and German, Nadezhda and Zhang, Siyu and Zhu, Yong-Guan and Rensing, Christopher},
  issn         = {1432-0614},
  keyword      = {Copper,Pathogenicity,Amoeba,Grazing resistance},
  language     = {eng},
  number       = {14},
  pages        = {5817--5824},
  publisher    = {Springer},
  series       = {Applied Microbiology and Biotechnology},
  title        = {Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"},
  url          = {http://dx.doi.org/10.1007/s00253-015-6749-0},
  volume       = {99},
  year         = {2015},
}