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Cost-effectiveness of maintenance treatment with a barrier-strengthening moisturizing cream in patients with atopic dermatitis in Finland, Norway and Sweden

Norrlid, Hanna; Hjalte, Frida; Lundqvist, Adam; Svensson, Åke LU and Ragnarson Tennvall, Gunnel LU (2016) In Acta Dermato-Venereologica 96(2). p.173-176
Abstract
Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active... (More)
Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active ingredients in all 3 countries. The result was confirmed in all but 1 sensitivity analysis. In conclusion, the barrier-strengthening moisturizer is cost-effective as maintenance therapy for patients with atopic dermatitis compared with a moisturizer with no active ingredients. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
96
issue
2
pages
173 - 176
publisher
Medical Journals Limited
external identifiers
  • pmid:26304099
  • scopus:84954472309
  • wos:000373943700005
ISSN
1651-2057
DOI
10.2340/00015555-2221
language
English
LU publication?
yes
id
d3c75c79-974b-4cca-aa6a-330e77cc4402 (old id 7834941)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26304099?dopt=Abstract
date added to LUP
2015-09-07 19:13:31
date last changed
2017-08-13 03:52:52
@article{d3c75c79-974b-4cca-aa6a-330e77cc4402,
  abstract     = {Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active ingredients in all 3 countries. The result was confirmed in all but 1 sensitivity analysis. In conclusion, the barrier-strengthening moisturizer is cost-effective as maintenance therapy for patients with atopic dermatitis compared with a moisturizer with no active ingredients.},
  author       = {Norrlid, Hanna and Hjalte, Frida and Lundqvist, Adam and Svensson, Åke and Ragnarson Tennvall, Gunnel},
  issn         = {1651-2057},
  language     = {eng},
  number       = {2},
  pages        = {173--176},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Cost-effectiveness of maintenance treatment with a barrier-strengthening moisturizing cream in patients with atopic dermatitis in Finland, Norway and Sweden},
  url          = {http://dx.doi.org/10.2340/00015555-2221},
  volume       = {96},
  year         = {2016},
}