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Acute Unilateral Vestibulopathy.

Strupp, Michael and Magnusson, Måns LU (2015) In Neurologic Clinics 33(3). p.669-669
Abstract
Normal vestibular end organs generate an equal resting-firing frequency of the axons, which is the same on both sides under static conditions. An acute unilateral vestibulopathy leads to a vestibular tone imbalance. Acute unilateral vestibulopathy is defined by the patient history and the clinical examination and, in unclear cases, laboratory examinations. Key signs and symptoms are an acute onset of spinning vertigo, postural imbalance and nausea as well as a horizontal rotatory nystagmus beating towards the non-affected side, a pathological head-impulse test and no evidence for central vestibular or ocular motor dysfunction. The so-called big five allow a differentiation between a peripheral and central lesion by the bedside examination.... (More)
Normal vestibular end organs generate an equal resting-firing frequency of the axons, which is the same on both sides under static conditions. An acute unilateral vestibulopathy leads to a vestibular tone imbalance. Acute unilateral vestibulopathy is defined by the patient history and the clinical examination and, in unclear cases, laboratory examinations. Key signs and symptoms are an acute onset of spinning vertigo, postural imbalance and nausea as well as a horizontal rotatory nystagmus beating towards the non-affected side, a pathological head-impulse test and no evidence for central vestibular or ocular motor dysfunction. The so-called big five allow a differentiation between a peripheral and central lesion by the bedside examination. The differential diagnosis of peripheral labyrinthine and vestibular nerve disorders mimicking acute unilateral vestibulopathy includes central vestibular disorders, in particular "vestibular pseudoneuritis" and other peripheral vestibular disorders, such as beginning Menière's disease. The management of acute unilateral vestibulopathy involves (1) symptomatic treatment with antivertiginous drugs, (2) causal treatment with corticosteroids, and (3) physical therapy. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Neurologic Clinics
volume
33
issue
3
pages
669 - 669
publisher
Elsevier
external identifiers
  • wos:000360324800011
  • pmid:26231279
  • scopus:84938261083
ISSN
0733-8619
DOI
10.1016/j.ncl.2015.04.012
language
English
LU publication?
yes
id
fe24dcf5-8bcd-4801-aa6b-38acdebe6821 (old id 7845140)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26231279?dopt=Abstract
date added to LUP
2015-09-03 18:56:31
date last changed
2017-11-19 03:13:01
@article{fe24dcf5-8bcd-4801-aa6b-38acdebe6821,
  abstract     = {Normal vestibular end organs generate an equal resting-firing frequency of the axons, which is the same on both sides under static conditions. An acute unilateral vestibulopathy leads to a vestibular tone imbalance. Acute unilateral vestibulopathy is defined by the patient history and the clinical examination and, in unclear cases, laboratory examinations. Key signs and symptoms are an acute onset of spinning vertigo, postural imbalance and nausea as well as a horizontal rotatory nystagmus beating towards the non-affected side, a pathological head-impulse test and no evidence for central vestibular or ocular motor dysfunction. The so-called big five allow a differentiation between a peripheral and central lesion by the bedside examination. The differential diagnosis of peripheral labyrinthine and vestibular nerve disorders mimicking acute unilateral vestibulopathy includes central vestibular disorders, in particular "vestibular pseudoneuritis" and other peripheral vestibular disorders, such as beginning Menière's disease. The management of acute unilateral vestibulopathy involves (1) symptomatic treatment with antivertiginous drugs, (2) causal treatment with corticosteroids, and (3) physical therapy.},
  author       = {Strupp, Michael and Magnusson, Måns},
  issn         = {0733-8619},
  language     = {eng},
  number       = {3},
  pages        = {669--669},
  publisher    = {Elsevier},
  series       = {Neurologic Clinics},
  title        = {Acute Unilateral Vestibulopathy.},
  url          = {http://dx.doi.org/10.1016/j.ncl.2015.04.012},
  volume       = {33},
  year         = {2015},
}