Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Tissue Properties from Quantitative MRI

Helms, Gunther LU orcid (2015) 1. p.287-294
Abstract
Quantitative MRI provides reproducible ‘maps’ of biophysical parameters that govern MRI contrast. The basic molecular mechanisms – exchange and diffusion – are outlined in a simple way to explain the major determinants of MRI contrast in the brain (macromolecules, myelinated axons, and iron) and the influence of microscopic subspaces (intracellular, vascular, extracellular–extravascular, and myelin sheaths). The most important parameters in brain MRI are explained and related to microscopic properties of brain tissue, offering an introduction into relaxometry and susceptibility mapping. Diffusion and perfusion imaging and amide proton transfer are briefly covered.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Amide proton transfer, human brain, Magnetic susceptibility, Magnetization transfer, Relaxometry, Myelin, Ferritin, Exchange, Dynamic contrast enhancement, Diffusion
host publication
Brain Mapping: An Encyclopedic Reference
editor
Toga, Arthur W.
volume
1
pages
287 - 294
publisher
Elsevier
external identifiers
  • scopus:84943242930
ISBN
978-0123970251
language
English
LU publication?
yes
id
9cd453fe-ea6f-4c43-90be-8ebce5edc426 (old id 7854722)
alternative location
https://www.sciencedirect.com/science/article/pii/B9780123970251002979?via%3Dihub
date added to LUP
2016-04-04 12:24:40
date last changed
2022-03-31 19:51:33
@inbook{9cd453fe-ea6f-4c43-90be-8ebce5edc426,
  abstract     = {{Quantitative MRI provides reproducible ‘maps’ of biophysical parameters that govern MRI contrast. The basic molecular mechanisms – exchange and diffusion – are outlined in a simple way to explain the major determinants of MRI contrast in the brain (macromolecules, myelinated axons, and iron) and the influence of microscopic subspaces (intracellular, vascular, extracellular–extravascular, and myelin sheaths). The most important parameters in brain MRI are explained and related to microscopic properties of brain tissue, offering an introduction into relaxometry and susceptibility mapping. Diffusion and perfusion imaging and amide proton transfer are briefly covered.}},
  author       = {{Helms, Gunther}},
  booktitle    = {{Brain Mapping: An Encyclopedic Reference}},
  editor       = {{Toga, Arthur W.}},
  isbn         = {{978-0123970251}},
  keywords     = {{Amide proton transfer; human brain; Magnetic susceptibility; Magnetization transfer; Relaxometry; Myelin; Ferritin; Exchange; Dynamic contrast enhancement; Diffusion}},
  language     = {{eng}},
  pages        = {{287--294}},
  publisher    = {{Elsevier}},
  title        = {{Tissue Properties from Quantitative MRI}},
  url          = {{https://lup.lub.lu.se/search/files/75580228/15_BMER_00297_helms.pdf}},
  volume       = {{1}},
  year         = {{2015}},
}